… The expression of recombinant proteins in mammalian cells is presently hampered by the
… expression between individual cell clones or transgenic animals. Variability of expression …

… plasmids have been developed for transient gene expression (TGE) containing the SV40
or EBNA1 origins of replication [14] to aid episomal replication of plasmids and potentially …

… a potentially rich source of genes for introduction into mammalian cells. Accordingly, we …
animal cells with bacterial genes. For a variety of reasons, the Escherichia coli gene (Ecogpt, …

… in a single cell culture in mammalian cells, and we apply this system for the multi-chromatic
control of angiogenic signaling processes. This portfolio of optogenetic tools enables the …

… The methylation of mammalian genomic DNA is catalyzed by DNA methyltransferases (… of
chromatin remodeling and gene expression regulation. The mammalian DNMTs are DNMT1, …

… expressing long complementary RNAs in mammalian cells, with the potential to form dsRNA
and regulate specific gene expression. … transgene and endogenous genes. The suppressive …

… core promoters for mammalian gene expression, including promoters with viral, mammalian,
and … We demonstrate that the panel of promoters provides a wide range of gene expression …

… Here we describe repressible (PipOFF) as well as inducible (PipON) systems for
regulated gene expression in mammalian cells, based on the repressor Pip (pristinamycin-induced …

… to potent inhibition of gene or vector expression, owing to the … the efficient induction of gene
expression, owing to inhibition … expression is shown in a variety of mammalian cell lines and …

… Molecular data rapidly accumulating on the regulation of gene expression by amino acids
in mammalian cells highlight the large variety of mechanisms that are involved. Transcription …