Exogenous control of mammalian gene expression through modulation of RNA self-cleavage

L Yen, J Svendsen, JS Lee, JT Gray, M Magnier… - Nature, 2004 - nature.com
… to potent inhibition of gene or vector expression, owing to the … the efficient induction of gene
expression, owing to inhibition … expression is shown in a variety of mammalian cell lines and …

Control of mammalian gene expression by amino acids, especially glutamine

C Brasse‐Lagnel, A Lavoinne, A Husson - The FEBS journal, 2009 - Wiley Online Library
… Molecular data rapidly accumulating on the regulation of gene expression by amino acids
in mammalian cells highlight the large variety of mechanisms that are involved. Transcription …

Advancements in mammalian cell transient gene expression (TGE) technology for accelerated production of biologics

S Gutiérrez-Granados, L Cervera… - Critical reviews in …, 2018 - Taylor & Francis
Transient gene expression (TGE) in animal cell cultures has been used for almost 30 years
to produce milligrams and grams of recombinant proteins, virus-like particles and viral vectors…

Cadmium, gene regulation, and cellular signalling in mammalian cells

D Beyersmann, S Hechtenberg - Toxicology and applied pharmacology, 1997 - Elsevier
… We summarize here a few results that are most ous types of cultured mammalian cells (…
cellular signalling pathways involved in the control of gene expression in mammalian cells. The …

Gene expression and cell fusion analyzed by lacZ complementation in mammalian cells.

WA Mohler, HM Blau - … of the National Academy of Sciences, 1996 - National Acad Sciences
… reporter genes provide biological indicators of coincident expression of proteins in cells. We
… the Escherichia coli lacZ gene for use in mammalian cells. Enzymatic activity detectable by …

The regulation of mRNA stability in mammalian cells: 2.0

X Wu, G Brewer - Gene, 2012 - Elsevier
… In a 2001 issue of Gene, we reviewed the regulation of mRNA stability in mammalian cells.
… major frontier in the field of posttranscriptional gene expression: the roles of noncoding RNAs …

Generation of mammalian cells stably expressing multiple genes at predetermined levels

X Liu, SN Constantinescu, Y Sun, JS Bogan… - Analytical …, 2000 - Elsevier
… at controlled levels in mammalian cells is important for investigating their … stable expression
of a gene of interest in cultured mammalian cells, yet it is very difficult to obtain expression of …

Expression of antibody genes in nonlymphoid mammalian cells

CR Bebbington - Methods, 1991 - Elsevier
… levels reported were rather low, the ability of nonlymphoid cell lines to assemble and …
expression. Chinese hamster ovary (CHO) cells are widely used for recombinant gene expression, …

mRNA stability in mammalian cells

J Ross - Microbiological reviews, 1995 - Am Soc Microbiol
… how mRNA decay rates inffuence gene expression. The topic is important, because mRNA
stability inffuences gene expression in virtually all organisms, from bacteria to mammals. In …

Amplification and expression of genes associated with multidrug resistance in mammalian cells

KW Scotto, JL Biedler, PW Melera - Science, 1986 - science.org
… Although MDRA gene expression was elevated in each of the multidrug-resistant cell lines
tested, we could not establish a clear relation between the amount of gene expression and …