Effects of nicotinic acid on gene expression: potential mechanisms and implications for wanted and unwanted effects of the lipid-lowering drug

I Kang, SW Kim, JH Youn - The Journal of Clinical …, 2011 - academic.oup.com
… has widespread effects on gene expression in major tissues of … that the effects of NA on
gene expression may explain some of the … NA effects on gene expression and discuss potential …

Widespread effects of nicotinic acid on gene expression in insulin-sensitive tissues: implications for unwanted effects of nicotinic acid treatment

S Choi, H Yoon, KS Oh, YT Oh, YI Kim, I Kang, JH Youn - Metabolism, 2011 - Elsevier
gene expression was evaluated using a microarray analysis. Nicotinic acid had widespread
effects on gene expression … of genes affected by NA greatly exceeded that of genes affected …

[HTML][HTML] Nicotinic acid inhibits hepatic APOA gene expression: studies in humans and in transgenic mice

I Chennamsetty, KM Kostner, T Claudel, M Vinod… - Journal of Lipid …, 2012 - ASBMB
Elevated plasma lipoprotein(a) (LPA) levels are recognized as an independent risk factor for
cardiovascular diseases. Our knowledge on LPA metabolism is incomplete, which makes it …

Influence of dietary nicotinic acid supplementation on lipid metabolism and related gene expression in two distinct broiler breeds of female chickens

RR Jiang, GP Zhao, JP Zhao, JL Chen… - Journal of animal …, 2014 - Wiley Online Library
… This study aimed to evaluate the influence of supplemental dietary nicotinic acid (NA) on
lipid metabolism and hepatic expression of related genes in female chickens of two distinct …

Nicotinic acid modulates Legionella pneumophila gene expression and induces virulence traits

RL Edwards, A Bryan, M Jules, K Harada… - Infection and …, 2013 - Am Soc Microbiol
… by which nicotinic acid modulates these two-component systems is not understood. … that
nicotinic acid might similarly modulate the expression of L. pneumophila transmission genes

Nicotinic acid induces apolipoprotein AI gene expression in HepG2 and Caco-2 cell lines

MJ Haas, AR Alamir, S Sultan, JM Chehade… - Metabolism, 2011 - Elsevier
… The latter study suggests that nicotinic acid may be increasing the expression of apo AI gene
of various concentrations of nicotinic acid on apo AI gene expression in HepG2 and Caco-2 …

Continuous 24-h nicotinic acid infusion in rats causes FFA rebound and insulin resistance by altering gene expression and basal lipolysis in adipose tissue

YT Oh, KS Oh, YM Choi, A Jokiaho… - American Journal …, 2011 - journals.physiology.org
… to alter gene expression in major tissues involved in lipid metabolism, including adipose
tissue. Therefore, we were particularly interested in assessing changes in gene expression in …

Gene expression in tobacco low-nicotine mutants.

N Hibi, S Higashiguchi, T Hashimoto… - The Plant Cell, 1994 - academic.oup.com
… to the l-methyl-A'-pyrrolinium cation, which is condensed with nicotinic acid or its derivative
by an unknown enzyme to form nicotine (Hashimoto and Yamada, 1993). Quinolinic …

Nicotinic acid: pharmacological effects and mechanisms of action

A Gille, ET Bodor, K Ahmed… - Annu. Rev. Pharmacol …, 2008 - annualreviews.org
… of nicotinic acid has gained momentum. In this review, we summarize the pharmacological
effects of nicotinic acid … discovered receptor in the pharmacological actions of nicotinic acid. …

Molecular identification of nicotinic acid receptor

T Soga, M Kamohara, J Takasaki, S Matsumoto… - Biochemical and …, 2003 - Elsevier
… In line with this course of research, we managed to identify an endogenous receptor for
nicotinic acid, which is a Gi/o-coupled receptor expressing in the adipose tissue. …