… support the theory that prognostic gene-expression signatures are present at diagnosis in
the bulk population of leukemic cells and that the use of gene-expression profiling will improve …

… utility of gene expression profiles, including the identification of prognostic subclasses (6–15…
studies, followed by the development of gene expression–based diagnostics adapted to the …

… We hypothesized that some nonMBC might have an expression profile close to that of
MBC for these genes, and perhaps better prognosis than other nonMBC. Based on this 368-gene …

… Stratification of melanoma patients into clinically important subclasses … a prognostic role
of immune gene expression (9), we investigated the prognostic effect of a priori defined genes …

… To assess heterogeneity of the gene expression profile … using stage-specific gene expression
profiles. NMF analysis … the biological functions of the gene expression profiles, we used GO …

… To make a clinically useful classification by gene expression profiling, we used a 40 … gene
expression profiles for 48 lung SCCs. Firstly, we sought to identify genes whose expression …

… gene expression profiles, defined using candidate gene arrays, can identify clinically relevant
tumour subgroups, significantly contributing to the refinement of poor-prognosis … subclasses…

… role of gene expression profiling in breast cancer by identifying new prognostic subclasses
unidentifiable by conventional parameters and new prognostic and/or predictive gene …

… leukemia (AML) subgroups with favorable prognosis. However, there exists substantial …
To improve the molecular characterization we profiled gene expression in a large series (n …

… On the basis of these principles, a molecular classification system and prognostic multigene
classifiers based on microarrays or derivative technologies have been developed and are …