Viral vectors in gene therapy

AE Smith - Annual review of microbiology, 1995 - go.gale.com
viral vectors for human gene therapy are considered. Although viral vectors are an obvious
starting point because viruses … , by the same token the viral hosts have evolved sophisticated …

Viral vectors for gene therapy

PD Robbins, H Tahara, SC Ghivizzani - Trends in biotechnology, 1998 - cell.com
vector systems used for genetherapeutic applications - viral and nonviral. For the most part,
viral vectors are more effective than nonviral vectorsgene transfer, but they have associated …

Viral vectors, tools for gene transfer in the nervous system

WT Hermens, J Verhaagen - Progress in neurobiology, 1998 - Elsevier
… of viral vectors and to discuss the advantages and disadvantages of the viral vector systems
currently in use for gene … Secondly, we give an overview of the performance of these vectors

Viral vectors for gene delivery to the central nervous system

TB Lentz, SJ Gray, RJ Samulski - Neurobiology of disease, 2012 - Elsevier
virus, retrovirus, adenovirus and herpesvirus vectors are … that have made these viruses
effective tools for gene delivery with … vector and which viral vectors can provide these features. …

Viral vectors: a look back and ahead on gene transfer technology

L Vannucci, M Lai, F Chiuppesi, L Ceccherini-Nelli… - New …, 2013 - arpi.unipi.it
viral vectors that are now used in vitro and in vivo to study cellular gene function, correct
genetic defects (geneviral vectors, and their advantages, limitations and principal applications. …

Viral vectors for gene delivery to the nervous system

BL Davidson, XO Breakefield - Nature Reviews Neuroscience, 2003 - nature.com
… the genetic constitution of … virus vectors that can efficiently deliver genes to neurons and
other neural cells in vitro and in vivo. These vectors allow us to monitor neurobiological functions

Rationale for developing new virus vectors to analyze gene function in grasses through virus-induced gene silencing

H Ramanna, XS Ding, RS Nelson - Virus-induced gene silencing …, 2013 - Springer
… strengths and weaknesses in current virus–grass host systems. We describe ways to improve
current virus vectors and the potential of other grass-infecting viruses for VIGS studies. This …

Gene therapy with viral vectors

NA Kootstra, IM Verma - Annual review of pharmacology and …, 2003 - annualreviews.org
… This review focuses on viral vectors commonly used in gene therapy studies.Their specific
properties are summarized in Table1. Although remarkable progress has been made in the …

Viral vectors for gene transfer

YH Chen, MS Keiser… - Current protocols in mouse …, 2018 - Wiley Online Library
… competent Ad is a promising viral vector for cancer therapy (Rosewell Shaw & Suzuki, 2016).
In summary, viral vectors provide a valuable tool to deliver a genetic payload to desired cell …

Gene therapy using adeno-associated virus vectors

S Daya, KI Berns - Clinical microbiology reviews, 2008 - Am Soc Microbiol
… Adeno-associated virus (AAV) vectors are currently among the most frequently used viral
vectors for gene therapy. At recent meetings of the American Society for Gene Therapy, nearly …