Analysis of a large prostate cancer family identifies novel and recurrent gene fusion events providing evidence for inherited predisposition
K Raspin, DE O'Malley, JR Marthick, S Donovan… - … Prostate, 2022 - Wiley Online Library
… and limited scope of gene fusion studies in familial PrCa, the … and diversity of gene fusions
in multiple prostate tumours from … fusions in PcTas9 was 64.3% and involved five distinct gene …
in multiple prostate tumours from … fusions in PcTas9 was 64.3% and involved five distinct gene …
Recurrent gene fusions in prostate cancer
… expression of ERG–ETV1 may be a key molecular event in a subset of prostate cancers. …
expression of other Ets family genes and discovered more gene fusions, such as TMPRSS2– …
expression of other Ets family genes and discovered more gene fusions, such as TMPRSS2– …
ETS fusion genes in prostate cancer
DG Tandefelt, J Boormans, K Hermans… - … -related cancer, 2014 - erc.bioscientifica.com
… the family of ETS transcription factors. At lower frequency, other members of this gene
family … Although all other ETS gene fusion events are between genes that map on different …
family … Although all other ETS gene fusion events are between genes that map on different …
ETS gene fusions in prostate cancer
JP Clark, CS Cooper - Nature Reviews Urology, 2009 - nature.com
… gene family members are common events in human prostate … event in prostate cancer, the
expression of ETS gene fusions … gene expression has been reported in metastatic prostate …
expression of ETS gene fusions … gene expression has been reported in metastatic prostate …
Common gene rearrangements in prostate cancer
… Since the initial discovery of ETS fusions in prostate cancer, several recent studies have
identified fusion events involving additional ETS family members (ie, ELK4, 9,10 ) novel 5′ (ie, …
identified fusion events involving additional ETS family members (ie, ELK4, 9,10 ) novel 5′ (ie, …
Re-evaluate fusion genes in prostate cancer
… The top candidates include ETS gene family members: ERG (26 … fusion genes using TCGA
prostate cancer cohort Thousands of fusion events have been reported in prostate cancer. …
prostate cancer cohort Thousands of fusion events have been reported in prostate cancer. …
Next-generation sequencing reveals novel rare fusion events with functional implication in prostate cancer
I Teles Alves, T Hartjes, E McClellan, S Hiltemann… - Oncogene, 2015 - nature.com
… MPP5 is a member of the membrane-associated guanylate kinase family and contributes
to the establishment of cell polarity in mammals, which is crucial for tissue organization and …
to the establishment of cell polarity in mammals, which is crucial for tissue organization and …
Recurrent gene fusions in prostate cancer: their clinical implications and uses
D Hessels, JA Schalken - Current urology reports, 2013 - Springer
… Gene fusions involving other ETS family members or members of the RAS-RAF signalling …
, and currently gene fusions have to be considered as stochastic events for which DNA double-…
, and currently gene fusions have to be considered as stochastic events for which DNA double-…
Prostate cancer subtyping and differential methylation analysis based on the ETS family of transcription factors fusion genes
W Niu, G Li, T Zhang, L Ma - Scientific Reports, 2024 - nature.com
… In this study, we proposed considering the ETS family gene fusions in … fusion events of
PCa fusion genes were mainly concentrated on chromosomes 1, 4, and 21, with fusion events …
PCa fusion genes were mainly concentrated on chromosomes 1, 4, and 21, with fusion events …
[HTML][HTML] Overview of research on fusion genes in prostate cancer
C Song, H Chen - Translational Cancer Research, 2020 - ncbi.nlm.nih.gov
… In addition to the ERG and ETV1 genes, other members of the ETS family were also … The
high-frequency of the USP9Y-TTTY15 fusion suggested that it might be a physiologic event and …
high-frequency of the USP9Y-TTTY15 fusion suggested that it might be a physiologic event and …
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