… role of a bonafide mitochondrial gene mutation in cancer. [Cancer Res 2008;68(3):700–06] …
the role of mitochondrial gene mutation in tumor development. Mitochondria are the key …

… and nuclear gene mutations has been partially responsible for the steady increase in the
number of identified mutations in patients suspected to have dysfunctional mitochondria (see …

… to the possibility of a cytochrome b gene mutation. Confirmation of the … cytochrome b
gene mutations in seven patients, we believe that somatic mutations in this mitochondrial gene …

… We searched these genes, as well as other mitochondrial genes, for mutations that might …
missense mutations in the mitochondrial CO1 and CO2 genes but not the CO3 gene were …

… of DNA mutations in the mitochondrial encoded cytochrome c-oxidase I and II genes in 16/…
Gatterman et al (1997) described mitochondrial DNA mutations in cytochrome c-oxidase I in …

… Furthermore, the amount of cytochrome b was greatly reduced in mitochondria isolated
from fibroblasts. The child was reported to have undergone good clinical recovery, with neither …

… Mutation screening revealed compound heterozygosity for SCO1 gene mutations in the
patients. The mutated allele, inherited from the father, harbored a 2-bp frameshift deletion (ΔGA; …

… We describe a novel MTCYB gene mutation in a patient with muscle weakness and muscle
… III of the mitochondrial respiratory chain. A pathogenic role for the 15 699 G→C mutation is …

… ,ic cell genetic and biochemical studies indicated t)hat the resistance phenotypes were encoded
by mutations within the mitochondrial cytochrome b gene:. … t>he Gly23I residue of the cyt,…

… hyperventilation and hypocapnia of patients with Leigh syndrome associated with SURF1
gene mutations as a cause of low serum bicarbonates. J Inherit Metab Dis 24: 707-714, 2001. …