… In this review, we summarize genetic factors that have recently been identified impede …
models of human oocytes with zona pellucida gene mutations and mouse oocytes with zona …

… genes and do not affect spermatogenesis [9]. These studies have uncovered a number of
genes that can lead to oocyte maturation … that mtDNA mutations are one of genetic factors …

… maturation arrest. We confirmed that TUBB8 gene mutations occur in a high proportion of
infertile women with oocyte maturation arrest. We identified two novel …

… mutation confirms the diagnosis of oocyte maturation arrest. At present, the primary infertile
patients with oocyte maturation … We hope the problem of oocyte maturation arrest can be …

… The prevalence of TUBB8 mutations in 11 infertile women with oocyte maturation defects
was established in this study by genetic analysis. We found three novel variants (c.717C > G; (p.…

… Our results support that oocyte maturation defects produced by TUBB8 mutations are not …
reported in a Chinese female with oocyte maturation arrest as de novo mutation [Citation7]. …

… of human oocyte maturation arrest have been reported in the literature. Oocyte maturation
arrest … I, and metaphase II stage, but little is known about the underlying genetic pathology. …

… in affected individuals’ oocytes, we provide evidence that mutations in PATL2 lead to …
PATL2 mutations in oocyte maturation arrest and expand our understanding of the genetic …

… is observed in Caenorhabditis elegans mutants with severe meiotic … , mutations in multiple
SAC genes do not affect cyclin B levels or chromosome segregation in Drosophila oocytes 78 …

… mutations, we also identified other new types of genetic … as arrest in oocyte maturation and
early embryonic development. In this … missense mutations causing a variety of novel oocyte …