Choline acetyltransferase: the structure, distribution and pathologic changes in the central nervous system

Y Oda - Pathology international, 1999 - Wiley Online Library
… and gene structure, this unusual gene organization is termed ‘cholinergic gene locus’. … (a)
Immunohistochemistry and (b) in situ mRNA hybridization studies of choline acetyltransferase (…

A unique gene organization for two cholinergic markers, choline acetyltransferase and a putative vesicular transporter of acetylcholine.

S Bejanin, R Cervini, J Mallet, S Berrard - Journal of Biological Chemistry, 1994 - ASBMB
… In the present work, we provide evidence that the gene encoding a putative rat vesicular
ACh transporter lies within the first intron of the ChAT gene and in the same transcriptional …

Genomic Organization of Drosophila Choline Acetyltransferase

H Sugihara, V Andrisani… - Journal of …, 1991 - Wiley Online Library
… all the exons of this gene. The gene spans more than 26 kb of DNA and is organized into
eight exons containing … The only part of the ChAT gene not represented in our clones is a part …

Choline acetyltransferase: celebrating its fiftieth year

D Wu, LB Hersh - Journal of neurochemistry, 1994 - Wiley Online Library
… The genomic organization of the rat ChAT gene was first reported to consist of one 5’
noncoding exon and 14 coding exons, which account for the entire coding sequence and are …

Coregulation of two embedded gene products, choline acetyltransferase and the vesicular acetylcholine transporter

S Berrard, H Varoqui, R Cervini, M Israël… - Journal of …, 1995 - Wiley Online Library
… These two genes, whose products are required for the … gene organization and are consistent
with the existence of a coregulatory mechanism for the embedded ChAT and VAChT genes. …

Cloning and characterization of the choline acetyltransferase structural gene (cha-1) from C. elegans

A Alfonso, K Grundahl, JR McManus… - Journal of …, 1994 - Soc Neuroscience
genetic map, and that some of the transcripts may result from trans-splicing of the 22-base
spliced leader SLl. The cha-7 gene is organized … tibodies to choline acetyltransferase purified …

[HTML][HTML] Gene expression of mouse choline acetyltransferase. Alternative splicing and identification of a highly active promoter region.

H Misawa, K Ishii, T Deguchi - Journal of Biological Chemistry, 1992 - Elsevier
… of choline acetyltransferase gene contains elements that regulate neuron-specific expression
of choline acetyltransferase … revealed that the exon-intron organization and splicing pattern …

Cloning of the rat gene encoding choline acetyltransferase, a cholinergic neuron-specific marker.

M Hahn, SL Hahn, DM Stone… - Proceedings of the …, 1992 - National Acad Sciences
… With the gene organization presented here, it would be possible to investigate in detail
how … When the exon organization determined in this study is aligned with the amino acid …

Localization of choline acetyltransferase‐expressing neurons in Drosophila nervous system

K Yasuyama, PM Salvaterra - Microscopy research and …, 1999 - Wiley Online Library
gene encoding Drosophila vesicular acetylcholine transporter protein has also been identified
and shown to be organized … Drosophila melanogaster choline acetyltransferase gene. J …

[HTML][HTML] Association of the choline acetyltransferase gene with responsiveness to acetylcholinesterase inhibitors in Alzheimer's disease

H Yoon, W Myung, SW Lim, HS Kang, S Kim… - …, 2015 - thieme-connect.com
Choline acetyltransferase (ChAT) encoded by the gene CHAT synthesizes acetylcholine,
using choline … 2 CHAT organization and single-nucleotide polymorphism (SNP) locations (from …