… function of the NPC, the nuclear pore has been proposed to exert a more direct role in gene
expression through physical interactions of Nups with the nuclear genome (Akhtar & Gasser, …

… -transcriptional gene silencing and RNA processing. Together, these findings suggest that
the nuclear pore is utilized as a regulatory platform for a number of distinct gene expression …

… Nuclear pore complex (NPC)-mediated nucleocytoplasmic trafficking is essential for key …
, and gene regulation. The NPC has also been viewed as a nuclear architectural platform that …

… in a specialized nuclear pore environment (Fig. 1b). Thus juxtaposed, the 19S regulatory …
transcriptional competence of the target genes at nuclear pores. In the following paragraphs, …

… In the last few years there have been major advances in our understanding of the molecular
mechanisms that mediate gene-pore association and gene regulation at the nuclear …

… in gene regulation at the periphery, and possible functional roles associated with the spatial
positioning of chromosomes and genes in the nucleus. Silencing at the nuclear periphery …

… not required for gene-tethering to the nuclear periphery but for … genes that are already present
in the vicinity of nuclear pores. … regulate groups of related genes, sarcomeric and structural …

… interactions of CFTR with nuclear pore complexes (NPCs) and specifically with the nuclear
pore protein Nup93 [82], in agreement with the observed changes in nuclear positioning. TSA…

… Nuclear pore complexes (NPCs) composed of 30 individual nucleoporins form huge …
required to understand the complexity of the nuclear pore, whose function lies far beyond transport …

… has cytoplasmic, nuclear, and luminal aspects (120,169,189,333,370). … of nuclear pores
in the nuclear envelope are not well understood. The number and density of NPCs per nucleus …