… model for NPC function in transcriptional regulation. Thus, yeast TFs, together with nuclear
pore proteins, play a critical role in controlling the spatial organization of the yeast genome. …

… genes with respect to each other and with respect to nuclear … regulation is the movement
of genes from the nucleoplasm to … nuclear periphery through interaction with the nuclear pore …

… gene regulation at the nuclear envelope. Like many other research topics in the field of biology,
NPC-mediated genome regulation … genome-wide screening for NPC-interacting genes ( …

… , nuclear envelope and nuclear pores, each with distinct structures and functions. The
nuclear pore provides a gateway to the nucleus, … Nuclear compartments and gene regulation. …

… to the nuclear interior and contain active genes that regulate … Interactions between nuclear
pore components and genes … genes activated by nutrient availability localize to the nuclear …

… elegans nuclear pores in gene regulation, we performed total RNA-seq in embryos depleted
of NPP-13, the integral nucleoporin localized exclusively at the nuclear pore (Figures 1A …

… studies demonstrated that nuclear pore complexes might also contribute to gene regulation
via … For example, studies in yeast and Drosophila reveal that the nuclear pore complex might …

… inner membrane lies within the nucleus. Nuclear pores are created by a fusion of these two
membranes, thus defining the third membrane domain, the pore membrane. The resulting …

… The kaps then bind to nuclear pore complexes (NPCs) that form gateways across the NE
barrier. A series of binding and release steps then ensue, which facilitates transport of the kap …

… Figure 2 Molecular composition of the yeast and human nuclear pore complexes (NPCs).
Symmetric nucleoporins form the core region and are equally distributed on the cytoplasmic …