… new undescribed mutations. Our genetic assessment found putative pathologic mutations in
… Thus, the gene sequencing panel test deserves consideration in the clinical management of …

… ultra-deep sequencing using a narrow NGS panel on Ion Torrent … for the routine testing of
relevant tumour mutations in cfDNA. The … with that of NGS for mutational analysis in the blood of …

… of mutation detection and quantitative assessment of mutant alleles (21). NGS offers
nucleotide sequencing … -genome sequencing, whole-exome sequencing, and whole-transcriptome …

… , panel testing yields more accurate information on genetic … 2 alone and wide-spread testing
will help improve penetrance … Mutation detection has relied mostly on Sanger sequencing …

… In the meantime, mutations with high prevalence in primary tumors–the MMs from a
cancer-associated gene sequencing panel in the present study–may be one of the best surrogates …

… For some of the undiagnosed individuals in this cohort, we anticipate that causal mutation(s)
will be identified within the next 2–3 years without the need to perform additional …

… panel for melanoma mutation detection. Our panel includes the genes commonly mutated in
… The panel described here has been used in one patient with metastatic melanoma who had …

… Multiple-gene sequencing is entering practice, but its clinical … of a customized germline-DNA
sequencing panel for cancer-risk … -founder mutations panel; full sequencing with analysis of …

… Single-gene testing of FGFR3 detects mutations in 99% of achondroplasia patients and is
therefore the most efficient approach in terms of both cost and time. However, the physician …

… gene sequencing analyses to arrive at an exact diagnosis [9]. The most frequently used …
diagnostic method is sequential gene-by-gene mutation detection by Sanger sequencing. …