Bioinformatic Profiling Identifies a Fatty Acid Metabolism‐Related Gene Risk Signature for Malignancy, Prognosis, and Immune Phenotype of Glioma

Y Qi, D Chen, Q Lu, Y Yao, C Ji - Disease markers, 2019 - Wiley Online Library
… However, fatty acid metabolism related-gene set has not … of the fatty acid catabolic
metabolism-related gene risk signature … confirmed that fatty acid catabolic metabolism-related …

The fatty acid-related gene signature stratifies poor prognosis patients and characterizes TIME in cutaneous melanoma

S Hua, W Wang, Z Yao, J Gu, H Zhang, J Zhu… - Journal of Cancer …, 2024 - Springer
… The prognostic signature constructed in this study, based on six fatty acid-related genes, …
This signature can aid in patient risk stratification and provide guidance for clinical treatment …

Prognostic significance and immune landscape of a fatty acid metabolism-related gene signature in colon adenocarcinoma

X Liu, X Fang, L Lu, G Liu - Frontiers in genetics, 2022 - frontiersin.org
… Conclusion: This study provided novel insights into a fatty acid metabolism-related
signature in the prognosis an immune landscape of colon adenocarcinoma patients. …

Prognosis and dissection of immunosuppressive microenvironment in breast cancer based on fatty acid metabolism-related signature

Y Tang, W Tian, J Xie, Y Zou, Z Wang, N Li… - Frontiers in …, 2022 - frontiersin.org
… significance of fatty acid metabolism in … fatty acid metabolism-related genes (FMGs) and
identified the landscape of copy number variations and expression level among those genes. …

Construction of a fatty acid metabolism-related gene signature for predicting prognosis and immune response in breast cancer

L Qian, YF Liu, SM Lu, JJ Yang, HJ Miao, X He… - Frontiers in …, 2023 - frontiersin.org
… expression of genes related to fatty acid metabolism. … The differentially expressed genes
related to fatty acid … transcriptional regulators related to hub genes and construct an mRNA–…

Identification of fatty acids synthesis and metabolism-related gene signature and prediction of prognostic model in hepatocellular carcinoma

A Zhengdong, X Xiaoying, F Shuhui, L Rui… - Cancer Cell …, 2024 - Springer
… In our work, we utilized a gene signature of FASM to distinguish patients with different FASM
… the expression heterogeneity of hub gene ACACA and intercellular communication in HCC …

Genetic alterations in fatty acid transport and metabolism genes are associated with metastatic progression and poor prognosis of human cancers

A Nath, C Chan - Scientific reports, 2016 - nature.com
gene signature by analyzing the gene expression patterns of metabolic … fatty acid oxidation
genes altered in cancer cells, we included genes that may alter the availability of fatty acids to …

Fatty acid synthase expression defines distinct molecular signatures in prostate cancer

S Rossi, E Graner, P Febbo, L Weinstein… - Molecular Cancer …, 2003 - AACR
fatty acids (1). In particular, FAS is responsible for the last step of the endogenous fatty acid
synthesis, generation of fatty acid … Interestingly, no genes involved in the PI3K cascade were …

A potential fatty acid metabolism-related gene signature for prognosis in clear cell renal cell carcinoma

H Zhang, D Zhang, X Hu - Cancers, 2022 - mdpi.com
fatty acid metabolism (FAM) in ccRCC and construct a novel fatty acid metabolism-related
gene signature (… identifier (ImmuCellAI) algorithm and gene set variation analysis (GSVA) …

A fatty acid metabolism signature associated with clinical therapy in clear cell renal cell carcinoma

Z Wei, G Cheng, Y Ye, C Le, Q Miao, J Chen… - Frontiers in …, 2022 - frontiersin.org
… Using the fatty acid metabolism risk signature, the risk score … Therefore, the fatty acid
metabolism risk signature we … We screen differentially expressed genes in three fatty acid