Gene therapy for cartilage repair

H Madry, P Orth, M Cucchiarini - Cartilage, 2011 - journals.sagepub.com
… of the therapeutic molecule. In this review, we will focus on gene therapy approaches for
the repair of articular cartilage and meniscal fibrocartilage, including articular cartilage defects …

Stem cells and gene therapy for cartilage repair

UG Longo, S Petrillo, E Franceschetti… - Stem cells …, 2012 - Wiley Online Library
… regeneration is to obtain a hyaline-like cartilage repair tissue by transplantation of tissues or
… the role of gene therapy and mesenchimal stem cells for management of cartilage lesions. …

[HTML][HTML] The role of gene therapy in cartilage repair

EC Rodriguez-Merchan… - Archives of Bone and Joint …, 2019 - ncbi.nlm.nih.gov
… to the role of GT in cartilage repair was performed and the output … : cartilage repair AND
restoration and gene therapy AND … the role of GT in cartilage repair. The search parameters were …

Gene therapy for cartilage defects

M Cucchiarini, H Madry - The Journal of Gene Medicine: A …, 2005 - Wiley Online Library
… articular cartilage repairgene transfer to the problem of a focal articular cartilage defect.
In this review, we will focus on the basic scientific aspects of gene therapy for articular cartilage

Gene therapy for repair and regeneration of bone and cartilage

MW Grol, BH Lee - Current Opinion in Pharmacology, 2018 - Elsevier
… of tissue repair and regeneration in skeletal disease. In this review, we provide an overview
of viral gene therapies being developed for treatment of bone and cartilage pathologies, with …

Using gene therapy to protect and restore cartilage.

CH Evans, SC Ghivizzani, P Smith… - … Research (1976-2007 …, 2000 - journals.lww.com
… and thereby protect existing cartilage, they alone will not … gene therapy can be combined.
Such endeavors would be expedited if allografted cells were effective agents of cartilage repair

Articular cartilage repair by gene therapy using growth factor–producing mesenchymal cells

K Gelse, K von der Mark, T Aigner, J Park… - Arthritis & …, 2003 - Wiley Online Library
cartilage repair, the transplanted chondrocytes or perichondrium have been reported to
preferentially form fibrocartilage of minor quality instead of hyaline cartilage (8… to cartilage repair. …

Insulinlike growth factor-I gene therapy applications for cartilage repair.

AJ Nixon, BD Brower-Toland, SJ Bent… - … Research (1976-2007 …, 2000 - journals.lww.com
gene therapy is an emerging field that holds promise not only in cartilage repair but also in
muscle and skeletal repair… made in growth factor gene therapy for fracture repair, and to some …

Current concepts of gene therapy and cartilage repair

V Martinek, P Ueblacker… - The Journal of Bone & Joint …, 2003 - boneandjoint.org.uk
… , and therapeutic genes into lesions of articular cartilage … of gene transfer.This review
focuses on the basic premises underlying gene therapy and describes the current state of genetic

Gene therapy to enhance bone and cartilage repair in orthopaedic surgery

S Bougioukli, CH Evans, RK Alluri… - … Gene Therapy, 2018 - ingentaconnect.com
… In addition, gene therapy is being assessed … gene therapy to be a viable clinical entity for
the treatment of fracture nonunion and difficult bone repair scenarios, articular cartilage repair