… retinal function and improved vision, as determined by visual mobility in low light. The purpose
of this study was to determine whether gene therapy … of efficacy in terms of visual function. …

… This study represents achievement of the most substantial restoration of visual function
reported to date in an animal model of achromatopsia using a human gene construct, which has …

… caused by the mutations of RPE65 gene and gene therapy has been developed to be a …
changes in visual function and application of gene therapy in patients with RPE65-LCA. …

… is a progressive loss of photoreceptors and visual function, at a faster rate of degeneration
… /8 gene therapy vector can increase both photoreceptor survival and neuronal function in a …

… visual function using one or more measures, including visual … Future studies will involve fMRI
before and after gene therapy in … of gene therapy for LCA2. Finally, the fMRI finding that the …

… have been developed in the area of gene therapy for ocular disease. We also discuss the
challenges and opportunities facing gene therapy for ocular diseases, as well as its prospects. …

… In addition to anatomical preservation of both axons and somata, we found that gene
therapy using either Epo vector also preserved visual function in DBA/2J mice. F-VEPs were …

… to central atrophy and thus loss of central visual function. It has been recognized that STGD
is associated with mutations in the ABCA4 gene, which encodes a transport protein located …

… could rescue visual function by pharmacological intervention and gene transfer therapy in
… of oral administration of retinoids and gene therapy. Comparison of these two approaches is …

… an immune response when introduced via gene therapy. Furthermore, this method of …
expression and restoration of visual function, indicating that this therapy could be stable and …