Pathways for horizontal gene transfer in bacteria revealed by a global map of their plasmids

S Redondo-Salvo, R Fernández-López, R Ruiz… - Nature …, 2020 - nature.com
Plasmids can mediate horizontal gene transfer of antibiotic resistance, virulence genes, and
other adaptive factors across bacterial populations. Here, we analyze genomic composition …

Pathways for horizontal gene transfer in bacteria revealed by a global map of their plasmids

S Redondo, R Fernández López, R Ruiz, L Vielva… - 2020 - digital.csic.es
Plasmids can mediate horizontal gene transfer of antibiotic resistance, virulence genes, and
other adaptive factors across bacterial populations. Here, we analyze genomic composition …

Ecology drives a global network of gene exchange connecting the human microbiome

CS Smillie, MB Smith, J Friedman, OX Cordero… - Nature, 2011 - nature.com
… Quartet mapping and a gene loss analysis each support 99% of identified HGTs (…
relative to other environments, we compare gene transfer between the 1,183 human-associated …

Batch-learning self-organizing map identifies horizontal gene transfer candidates and their origins in entire genomes

T Abe, Y Akazawa, A Toyoda, H Niki… - Frontiers in microbiology, 2020 - frontiersin.org
gene transfer (HGT) has been widely suggested to play a critical role in the environmental
adaptation of microbes; however, the number and origin of the genes … Self-Organizing Map (…

Horizontal gene transfer: a critical view

CG Kurland, B Canback… - Proceedings of the …, 2003 - National Acad Sciences
gene transfers such as those encoding antibiotic-resistance phenotypes or pathogenesis
islands are often found in patches, ie, in small subpopulations of a global … Here we reveal maps

Inference and characterization of horizontally transferred gene families using stochastic mapping

O Cohen, T Pupko - Molecular biology and evolution, 2010 - academic.oup.com
mapping to infer branch-specific events. Our novel methodology allows us to infer and
quantify horizontal gene transfer … to the gene family at hand, for example, the global-mapping

Dissemination of antimicrobial resistance in microbial ecosystems through horizontal gene transfer

CJH Von Wintersdorff, J Penders… - Frontiers in …, 2016 - frontiersin.org
… resistance genes (… genetic elements and bacteriophages—form a reservoir of ARGs (the
resistome) from which pathogenic bacteria can acquire resistance via horizontal gene transfer (…

Adaptive evolution of bacterial metabolic networks by horizontal gene transfer

C Pál, B Papp, MJ Lercher - Nature genetics, 2005 - nature.com
gene transfer, with little contribution from gene duplicates. Networks grow by acquiring genes
… Accordingly, horizontally transferred genes are integrated at the periphery of the network, …

Genes and hypertension: from gene mapping in experimental models to vascular gene transfer strategies

AF Dominiczak, DC Negrin, JS Clark, MJ Brosnan… - …, 2000 - Am Heart Assoc
gene transfer of adenovirus encoding eNOS gene to vascular rings of mice with targeted
disruption (knockout) of this gene … be significantly improved by gene transfer in vessels in which …

Horizontal gene transfer and the evolution of bacterial and archaeal population structure

MF Polz, EJ Alm, WP Hanage - Trends in Genetics, 2013 - cell.com
… The madness we refer to is rapid gene turnover due to horizontal gene transfer (HGT) and
gene loss, which can lead to extensive genome differences among closely related bacteria …