Systems genetic analysis of osteoblast-lineage cells
G Calabrese, BJ Bennett, L Orozco, HM Kang… - … genetics, 2012 - journals.plos.org
… In contrast, little is known regarding the composition or function of gene networks within …
genes are organized into networks in osteoblasts. Towards this goal, we used microarray gene …
genes are organized into networks in osteoblasts. Towards this goal, we used microarray gene …
RANKL expression is related to the differentiation state of human osteoblasts
GJ Atkins, P Kostakis, B Pan, A Farrugia… - Journal of Bone and …, 2003 - academic.oup.com
… in human osteoblasts (NHBC), in terms of the pre‐osteoblast marker, STRO‐1, and the
mature osteoblast marker, alkaline phosphatase (AP), and the expression of genes involved in …
mature osteoblast marker, alkaline phosphatase (AP), and the expression of genes involved in …
Expression of microRNA-30c and its target genes in human osteoblastic cells by nano-bioglass ceramic-treatment
A Moorthi, S Vimalraj, C Avani, Z He… - International journal of …, 2013 - Elsevier
… miR-30c expression in human osteoblastic cells (MG63). … genes involved in negative
regulation of osteoblast differentiation. TGIF2 and HDAC4 were found to be its putative target genes …
regulation of osteoblast differentiation. TGIF2 and HDAC4 were found to be its putative target genes …
Gene array analysis of osteoblast differentiation
GR Beck Jr, B Zerler, E Moran - 2001 - AACR
… In this report we have used a gene array approach to monitor the expression of various
classes of genes in an osteoblast differentiation system. A frequently used agent of osteoblast …
classes of genes in an osteoblast differentiation system. A frequently used agent of osteoblast …
Transcriptional regulation of osteoblasts
… Major transcription factors that, based on genetic studies, are involved in osteoblast and
chondrocyte differentiation are included in this chart. Also shown is the sequential nature of …
chondrocyte differentiation are included in this chart. Also shown is the sequential nature of …
Normal human osteoblast‐like cells consistently express genes for insulin‐like growth factors I and II but transformed human osteoblast cell lines do not
R Okazaki, CA Conover, SA Harris… - Journal of Bone and …, 1995 - academic.oup.com
… In the present study we characterized various human osteoblastic cell models with regard
to IGF-I and I<iF-II gene expression. Of the six cell models tested, only normal hOB cells …
to IGF-I and I<iF-II gene expression. Of the six cell models tested, only normal hOB cells …
[HTML][HTML] Identification of novel genes in aging osteoblasts using next-generation sequencing and bioinformatics
YJ Chen, WA Chang, MS Huang, CH Chen, KY Wang… - Oncotarget, 2017 - ncbi.nlm.nih.gov
… During the aging process, impaired osteoblastic function is … genes in normal and aged
osteoblasts and to identify genes … and 22 differentially expressed genes were identified. Up-…
osteoblasts and to identify genes … and 22 differentially expressed genes were identified. Up-…
HIV protease inhibitors selectively induce gene expression alterations associated with reduced calcium deposition in primary human osteoblasts
… (hMSCs) differentiated into osteoblasts. Further, nelfinavir … in effects of different PIs on
osteoblast and osteoclast activity in … phenotypic alterations of a human osteoblast cell line …
osteoblast and osteoclast activity in … phenotypic alterations of a human osteoblast cell line …
The RUNX2 cistrome in osteoblasts: characterization, down-regulation following differentiation, and relationship to gene expression
MB Meyer, NA Benkusky, JW Pike - Journal of Biological Chemistry, 2014 - ASBMB
… both pre-osteoblastic MC3T3-E1 cells (POB) and their mature osteoblast progeny (OB),
characterized the two cistromes and assessed their relationship to changes in gene expression. …
characterized the two cistromes and assessed their relationship to changes in gene expression. …
The transcription factor osterix (SP7) regulates BMP6‐induced human osteoblast differentiation
… We show that Osterix regulates a set of ECM genes involved in terminal osteoblast
differentiation, and that one of those molecules, osteomodulin, promotes increased mineralization …
differentiation, and that one of those molecules, osteomodulin, promotes increased mineralization …