LOX-1: a critical player in the genesis and progression of myocardial ischemia

J Lü, JL Mehta - Cardiovascular drugs and therapy, 2011 - Springer
… In other studies, we showed that LOX-1 is involved in the genesis of oxidant stress and
inflammation during myocardial ischemia-reperfusion [40]. Acute myocardial ischemia is …

Oxidized LDL, LOX-1 and atherosclerosis

S Mitra, T Goyal, JL Mehta - Cardiovascular drugs and therapy, 2011 - Springer
… been shown to upregulate expression of LOX-1. In addition, ox-… and LOX-1 in genesis and
progression of atherosclerosis. … oxygen species and LOX-1 in the genesis of atherosclerosis …

Novel concepts in the genesis of hypertension: role of LOX-1

P Luo, M Yan, ED Frohlich, JL Mehta, C Hu - Cardiovascular drugs and …, 2011 - Springer
… It has become abundantly evident that ox-LDL is more important in the genesis and
progression of hypertension than native unmodified LDL [54]. Ox-LDL leads to endothelial …

LOX-1 and ROS, inseparable factors in the process of endothelial damage

V Lubrano, S Balzan - Free Radical Research, 2014 - Taylor & Francis
… a direct role of microcirculatory dysfunction in the genesis of target-organ damage in …
crucial risk factor for initiation and progression of atherosclerosis through OxLDL production …

Pro-oncogenic action of LOX-1 and its splice variant LOX-1Δ4 in breast cancer phenotypes

S Pucci, C Polidoro, C Greggi, F Amati, E Morini… - Cell Death & …, 2019 - nature.com
… Actually, previous observations on alterations of different and specific fatty-acid metabolic
enzymes in the genesis and progression of breast cancer, further categorize the relevance of …

LOX-1, oxidative stress and inflammation: a novel mechanism for diabetic cardiovascular complications

M Yan, JL Mehta, W Zhang, C Hu - Cardiovascular drugs and therapy, 2011 - Springer
… roles of LOX-1 in the development and progression of diabetic … related to LOX-1, on the
development and progression of … play important roles in the genesis of diabetic nephropathy. …

Roles of LOX-1 in microvascular dysfunction

V Lubrano, S Balzan - Microvascular Research, 2016 - Elsevier
… Microcirculation appears to have a relevant role in the genesis of target organ damage in
various … in the initiation of endothelial dysfunction and its further progression to atherosclerosis. …

Oxidative stress and lectin-like ox-LDL-receptor LOX-1 in atherogenesis and tumorigenesis

J Lu, S Mitra, X Wang, M Khaidakov… - Antioxidants & redox …, 2011 - liebertpub.com
… O xidative stress plays a significant role in the genesis and progression of atherosclerosis
… Ang II and LOX-1 might reduce the genesis of Ang II–induced cardiac remodeling (Fig. 11). …

Lectin-like, oxidized low-density lipoprotein receptor-1 (LOX-1): a critical player in the development of atherosclerosis and related disorders

JL Mehta, J Chen, PL Hermonat, F Romeo… - Cardiovascular …, 2006 - academic.oup.com
… expression and activation, which in turn participates, at lest in part, in the genesis of the
diminished endothelium-dependent vasorelaxation and induction of hypertension. …

LOX-1 and obesity

M Yan, JL Mehta, C Hu - Cardiovascular drugs and therapy, 2011 - Springer
… NF-κB as a critical transcription factor has an important role in the genesis of inflammation of
… of LOX-1 in adipose tissue, especially whether LOX-1 signaling can lead to the progression