… evidence for the role of natural selection in phenotypic evolution, theoretical investigation
of the selective effects of alleles contributing to adaptation is relatively new (reviewed in [ …

… selection, there is also a role for random effects. Chance may increase the frequency of
neutral or … Although the average effects of random genetic drift are predictable, the outcome of …

… adaptation, the genetic bases of adaptation, tradeoffs and the environmental specificity of
adaptation, … adaptation, the emergence and effects of mutator genotypes, and the process of …

… adaptation, whereby fixed genetic differences between populations account for variation in
traits like heat tolerance, must be distinguished from the processes in which genetic … effects of …

… ‐effect loci in allowing adaptation under low genetic variance … patches in our four core genetic
architecture regimes. nemo … the effects of accumulated mutations during adaptation to the …

… Here I define the reaction norm of a genotype as its breeding value, or total additive
genetic effect determined by the mean phenotype of its offspring (under random mating) as a …

… of large-effect deleterious mutation is essentially independent of N e and π s . So if adaptation
most often involved preexisting, large effect … Another important caveat is that the effective …

… For instance, to examine the effect of pleiotropy on the speed of adaptation after a sudden
environmental change, we consider the pleiotropic model that was recently proposed by …

… We used quantitative genetic individual-based simulations to model the effect of … With this
work, we propose a breeding strategy that effectively minimizes genetic adaptation to captivity: …

… genetic change raises an important possibility: in humans, genetic adaptation to new
environments or genetic … or cultural adaptation might also have an important effect on our ability to …