β-Lactamase-mediated resistance: a biochemical, epidemiological and genetic overview

GO Gutkind, J Di Conza, P Power… - Current pharmaceutical …, 2013 - ingentaconnect.com
… major class of β-lactamase including epidemiology, genetic, and biochemical evaluations. …
accumulated mutations leading to resistance to βlactamase inhibitors in different amino acid …

Genetic Context and Biochemical Characterization of the IMP-18 Metallo-β-Lactamase Identified in a Pseudomonas aeruginosa Isolate from the United States

L Borgianni, S Prandi, L Salden… - Antimicrobial agents …, 2011 - Am Soc Microbiol
biochemical characterization of IMP-18 is currently available. However, a rationale for a
detailed biochemical characterization … In this work, we investigated the genetic context of the bla …

Genetic and biochemical characterization of OXA-519, a novel OXA-48-like β-lactamase

L Dabos, P Bogaerts, RA Bonnin, A Zavala… - Antimicrobial agents …, 2018 - Am Soc Microbiol
… Class D β-lactamases (DBLs), or OXA-type β-lactamases (OXAs), form a very diverse …
genetic and biochemical levels. OXA-48, the main carbapenem-hydrolyzing class D β-lactamase (…

Genetic and Biochemical Characterization of an Acquired Subgroup B3 Metallo-β-Lactamase Gene, blaAIM-1, and Its Unique Genetic Context in Pseudomonas …

D Yong, MA Toleman, J Bell, B Ritchie… - Antimicrobial agents …, 2012 - Am Soc Microbiol
… A gene bank was created, and an MBL gene, designated bla AIM-1 , was cloned and fully
characterized. The encoded enzyme, AIM-1, is a group B3 MBL that has the highest level of …

Inhibitor-resistant TEM β-lactamases: phenotypic, genetic and biochemical characteristics

EB Chaibi, D Sirot, G Paul… - Journal of Antimicrobial …, 1999 - academic.oup.com
… This paper reviews the phenotypic, genetic and biochemical characteristics of IRT β-lactamases
in an attempt to shed light on the pressures that have contributed to their emergence. …

Molecular and Biochemical Characterization of a Novel Class A β-Lactamase (HER-1) from Escherichia hermannii

A Beauchef-Havard, G Arlet, V Gautier… - Antimicrobial agents …, 2003 - Am Soc Microbiol
… coli by its production of yellow pigment and by various biochemical characteristics (4, 10).
Moreover, E. hermannii is distinguished from other Escherichia species by its natural …

Genetic and biochemical characterization of OXA-535, a distantly related OXA-48-like β-lactamase

L Dabos, AB Jousset, RA Bonnin… - Antimicrobial Agents …, 2018 - Am Soc Microbiol
… characterize the biochemical properties of OXA-535 and investigate its genetic environment
… Our findings illustrate the increasing complexity of genetic vehicles at the origin of OXA-48-…

Molecular and Biochemical Characterization of VEB-1, a Novel Class A Extended-Spectrum β-Lactamase Encoded by an Escherichia coli Integron Gene

L Poirel, T Naas, M Guibert, EB Chaibi… - Antimicrobial agents …, 1999 - Am Soc Microbiol
biochemically characterized (27). Along with a plasmid location, some β-lactamase genes
may be encoded in gene … insight on the complex genetic variety of β-lactamases and of their …

Molecular and Biochemical Characterization of OXA-45, an Extended-Spectrum Class 2d′ β-Lactamase in Pseudomonas aeruginosa

MA Toleman, K Rolston, RN Jones… - Antimicrobial agents and …, 2003 - Am Soc Microbiol
Genetic analysis of this isolate identified two unique extended-spectrum β-lactamase genes.
One… Analysis of the bla OXA-45 gene and flanking DNA determined that the GC content was …

Molecular and Biochemical Characterization of the Natural Chromosome-Encoded Class A β-Lactamase from Pseudomonas luteola

B Doublet, F Robin, I Casin, L Fabre… - Antimicrobial agents …, 2010 - Am Soc Microbiol
gene, encoding the class A β-lactamasebiochemical characteristics of LUT-1. The presence,
nucleotide diversity, and location of the bla LUT gene were studied in five other genetically