Genetic architecture of gene expression traits across diverse populations

LS Mogil, A Andaleon, A Badalamenti… - … genetics, 2018 - journals.plos.org
… Summary statistics and predictive models of genePredictive models of gene expression
developed in this study and … future studies of complex trait genetics across diverse populations. …

Comparison of whole-genome prediction models for traits with contrasting genetic architecture in a diversity panel of maize inbred lines

C Riedelsheimer, F Technow, AE Melchinger - BMC genomics, 2012 - Springer
… WGP models were remarkable similar, even for traits with drastically deviating genetic
architecture… if the WGP model is selected according to the genetic architecture underlying the trait. …

The critical needs and challenges for genetic architecture studies in Africa

AR Martin, S Teferra, M Möller, EG Hoal… - … Opinion in Genetics & …, 2018 - Elsevier
… associations with phenotypes, build more generalizable genetic risk prediction models, and
better understand the genetic architecture of complex traits and diseases subject to varying …

Genetic architecture and genomic predictive ability of apple quantitative traits across environments

M Jung, B Keller, M Roth, MJ Aranzana… - Horticulture …, 2022 - academic.oup.com
… This most comprehensive genomic study in apple in terms of trait-environment combinations
provided knowledge of trait biology and prediction models that can be readily applied for …

Estimating the genetic architecture of quantitative traits

ZB Zeng, CH Kao, CJ Basten - Genetics Research, 1999 - cambridge.org
… QTL and estimating the genetic architecture are discussed. We also point out potential
problems and difficulties in resolving the details of the genetic architecture as well as other areas …

Genome-wide prediction of traits with different genetic architecture through efficient variable selection

V Wimmer, C Lehermeier, T Albrecht, HJ Auinger… - Genetics, 2013 - academic.oup.com
… Our results have major impact on the choice of statistical method needed to make
credible inferences about genetic architecture and prediction accuracy of complex traits. …

Effect of genetic architecture on the prediction accuracy of quantitative traits in samples of unrelated individuals

F Morgante, W Huang, C Maltecca, TFC Mackay - Heredity, 2018 - nature.com
prediction accuracy. Our results indicate that accounting for genetic architecture can improve
prediction … of sample size, genetic architecture and different genomic prediction models on …

Integration of high-throughput phenotyping, GWAS, and predictive models reveals the genetic architecture of plant height in maize

W Wang, W Guo, L Le, J Yu, Y Wu, D Li, Y Wang… - Molecular Plant, 2023 - cell.com
… and the genetic architecture of PH, as well as resources and predictive models that are …
for molecular design breeding and predicting maize varieties with ideal plant architectures. …

Accounting for Genetic Architecture Improves Sequence Based Genomic Prediction for a Drosophila Fitness Trait

U Ober, W Huang, M Magwire, M Schlather… - PLoS …, 2015 - journals.plos.org
genetic architecture assumed by the genomic best linear unbiased prediction model and the
true genetic architecture of … Indeed, we found that the predictive ability of the genomic best …

The genetic architecture of maize height

JA Peiffer, MC Romay, MA Gore, SA Flint-Garcia… - Genetics, 2014 - academic.oup.com
… But, from every subset of RILs selected to calibrate a prediction model, 10 bootstrap samples
were taken with replacement in a family-stratified manner, these samples were not disjoint. …