Genetic association of Alzheimer's disease with multiple polymorphisms in alpha-2-macroglobulin

AJ Saunders, L Bertram, K Mullin… - … molecular genetics, 2003 - academic.oup.com
… Based on the biological and genetic data … polymorphisms in A2M for genetic association
with AD (Table 1). Family-based association studies have been largely supportive of genetic

A genetic association between systemic lupus erythematosus and tumor necrosis factor alpha

AG Wilson, C Gordon, FS di Giovine… - European journal of …, 1994 - Wiley Online Library
… The TNF polymorphism that we describe lies within the promoter region of the … The
polymorphism screened in this study is the only one characterized so far in the human TNF-a gene. …

[HTML][HTML] TNF-α gene polymorphisms and expression

RR El-Tahan, AM Ghoneim, N El-Mashad - Springerplus, 2016 - Springer
association between the genetic polymorphisms in TNF-α and the development of autoimmune
diseases, and the relation between these polymorphisms … significant genetic association

Systematic review by meta-analyses on the possible role of TNF-α polymorphisms in association with Alzheimer's disease

D Di Bona, G Candore, C Franceschi, F Licastro… - Brain research …, 2009 - Elsevier
association of the common polymorphisms comprehensively defining the genetic variability
of the TNF-α gene … control genetic association studies. Available data suggested a significant …

Tumour necrosis factor alpha gene polymorphisms in rheumatoid arthritis: association with susceptibility to, or severity of, disease?

BM Brinkman, TW Huizinga, SS Kurban… - British journal of …, 1997 - academic.oup.com
… on gene expression [14]. In this study, the frequencies of the known TNF-a polymorphisms in
… In addition, we determined whether TNF-a polymorphisms are associated with parameters …

[HTML][HTML] A comprehensive review of genetic association studies

JN Hirschhorn, K Lohmueller, E Byrne… - Genetics in …, 2002 - nature.com
… We identified 268 genes that contain polymorphisms reported to be associated with 1 of
133 … whether genetic associations between polymorphisms and disease are significant. …

Association between− G308A tumor necrosis factor alpha gene polymorphism and schizophrenia

F Boin, R Zanardini, R Pioli, CA Altamura, M Maes… - Molecular …, 2001 - nature.com
genetic susceptibility to schizophrenia. We studied the distribution of −G308A TNFα gene
polymorphism … This biallelic base exchange polymorphism directly affects TNFα plasma levels. …

Genetic association of an (α2-macroglobulin (Val1000lle) polymorphism and Alzheimer's disease

A Liao, RM Nitsch, SM Greenberg… - … molecular genetics, 1998 - academic.oup.com
… an A2M polymorphism in Alzheimer's disease, the possibility remains that … genetic association
we observe reflects linkage with another mutation or polymorphism either in the A2M gene

Estrogen receptor alpha gene polymorphisms are associated with estradiol levels in postmenopausal women

SCE Schuit, FH de Jong, L Stolk… - European journal of …, 2005 - academic.oup.com
… There are limitations to genetic association studies. First, they can be influenced by
population stratification or heterogeneity. This is especially true for case-control studies in a …

Multiple alpha‐synuclein gene polymorphisms are associated with Parkinson's disease in a Norwegian population

R Myhre, M Toft, J Kachergus… - Acta Neurologica …, 2008 - Wiley Online Library
… In this study we have demonstrated that several genetic polymorphisms located across the
SNCA … The majority of genetic associations reported in the literature have been difficult to …