Genetic code evolution investigated through the synthesis and characterisation of proteins from reduced‐alphabet libraries

MS Newton, DJ Morrone, KH Lee, B Seelig - ChemBioChem, 2019 - Wiley Online Library
characterisation of proteins representing early points in the genetic code's evolution lends
… an important first step in investigating the early evolution of today's protein-dominated world. …

Characterisation of a non-canonical genetic code in the oxymonad Streblomastix strix

PJ Keeling, BS Leander - Journal of molecular biology, 2003 - Elsevier
… four protein-coding genesevolved non-canonical nuclear genetic codes, and our phylogenetic
analyses of α-tubulin, β-tubulin, elongation factor-1 α (EF-1 alpha), heat-shock protein 90 …

Origins of Genetic Coding: Self-Guided Molecular Self-Organisation

PR Wills - Entropy, 2023 - mdpi.com
… The origin of genetic coding is characterised as … protein-based genetic coding. This is true
whether we are discussing its maintenance in every living cell on the planet or its evolutionary

Recent evidence for evolution of the genetic code

S Osawa, TH Jukes, K Watanabe… - Microbiological reviews, 1992 - Am Soc Microbiol
… One of these gave rise to the genetic code corresponding to the viral protein sequence, …
Actually, the genomic G+C content is related to phylogeny and not to such phenotypic characters

Non-standard genetic codes define new concepts for protein engineering

AR Bezerra, AR Guimarães, MAS Santos - Life, 2015 - mdpi.com
… the evolution of the genetic code and highlight new concepts that can be used to manipulate
protein … Detailed characterization of natural reassignments was a key step for developing …

Aminoacyl-tRNA synthetases, the genetic code, and the evolutionary process

CR Woese, GJ Olsen, M Ibba, D Soll - … and molecular biology …, 2000 - Am Soc Microbiol
proteins to evolve, the selective advantage of their specificity being great. Thus, the evolutionary
history … and the horizontal gene transfer characteristics of these enzymes suggests other …

Yeast as a model organism for studying the evolution of nonstandard genetic codes

RM Silva, I Miranda, G Moura… - Briefings in Functional …, 2004 - academic.oup.com
… decoding involving an intermediary stage characterised by competition between non-sense …
may not express functional proteins in host organisms with the standard genetic code. This …

The smooth evolution of the universal genetic code. Main episodes

PH Pawlowski - International Journal of Sciences, 2019 - eprints.ibb.waw.pl
… in DNA, through RNA, to synthesized protein, during the gene expression process, what
guarantees the preservation of primary, and higher level, protein … and discontinuous character. It …

[图书][B] Who wrote the book of life?: A history of the genetic code

LE Kay - 2000 - books.google.com
DNA code, RNA code, or the protein code, though it also referred to the correlation between
nucleic acids and proteins… : formation or molding of mind and character, training, instruction (…

Protein evolvability under rewired genetic codes

H Rozhoňová, C Martí-Gómez, DM McCandlish… - bioRxiv, 2023 - biorxiv.org
… provide a quantitative characterization of protein phenotype for … We show that robust genetic
codes, ie genetic codes that … and, consequently, allow evolving populations to reach on …