Genetic determinants of bone density and fracture risk—state of the art and future directions

EL Duncan, MA Brown - The Journal of Clinical Endocrinology & …, 2010 - academic.oup.com
… the current understanding of the genetics of osteoporosis based on … : Most genes involved
in osteoporosis identified to date encode components of known pathways involved in bone

Genetic determinants of bone mass

L Audí, M García-Ramírez, A Carrascosa - Hormone Research in …, 1999 - karger.com
… VDR gene polymorphisms, the differences in bone density … genotypes for COL1A1 in
bone density were reduced in … and bone density may be mediated in part by a genetic effect …

Genetic influences on bone turnover, bone density and fracture

PJ Kelly, NA Morrison, PN Sambrook… - European journal of …, 1995 - academic.oup.com
… A major determinant of fracture risk is bone density, indepen… Bone density in later life is
contributed to by both peak bonegenetic determinants (22). Clearly, these possible common …

Heritable and life‐style determinants of bone mineral density

EA Krall, B Dawson‐Hughes - … of Bone and Mineral Research, 1993 - academic.oup.com
… heredity of bone density, that is, whether determinants are predominantly genetic or whether
… Dequeker J, Nijs J, Verstraeten A, Geusens P, Gevers G 1987 Genetic determinants of bone

Genetic and environmental determinants of bone mineral density in Chinese women

HHL Lau, MYM Ng, AYY Ho, KDK Luk, AWC Kung - Bone, 2005 - Elsevier
… by genetic and lifestyle factors. To assess the genetic and environmental determinants of
BMD … of 12 candidate gene loci and lifestyle risk factors on spine and hip BMD. The candidate …

Genetic determinant of trabecular bone score (TBS) and bone mineral density: a bivariate analysis

LT Ho-Pham, D Hans, MC Doan, LD Mai, TV Nguyen - Bone, 2016 - Elsevier
… of genetic influence on the variation in trabecular bone score (TBS). We found that genetic
… the co-variation between TBS and bone density is partially determined by genetic factors. …

Bone density determinants in elderly women: a twin study

L Dr. Flicker, JL Hopper, L Rodgers… - Journal of Bone and …, 1995 - academic.oup.com
genetic factors may not influence bone loss at that site. Although much of the above suggests
that genetic effects on bone density … G 1987 Genetic determinants of bone mineral content …

Genetic and environmental correlations between bone formation and bone mineral density: a twin study

M Harris, TV Nguyen, GM Howard, PJ Kelly, JA Eisman - Bone, 1998 - Elsevier
… by common genes and/or environmental factors is unknown. If BMD is modulated indirectly
by genetic factors that control bone turnover, the genetic loci responsible for bone turnover …

Interaction of genetic and environmental influences on peak bone density

PJ Kelly, JA Eisman, PN Sambrook - Osteoporosis international, 1990 - Springer
… strong familial and genetic influences on adult bone density with genetic factors estimated to
… in bone density [1-6]. Analysis of twin data also suggest that a single gene or set of genes is …

Genetic determinants of bone mass in adults. A twin study.

NA Pocock, JA Eisman, JL Hopper… - The Journal of …, 1987 - Am Soc Clin Investig
… mass in the spine and proximal femur in adults and confirms the previously reported genetic
contribution to upper limb bone mass. The smaller genetic determinant of bone density in …