Genetic determinants of renal transplant outcome: where do we stand?

PJ Phelan, PJ Conlon, MA Sparks - Journal of nephrology, 2014 - Springer
Kidney transplantation has become the preferred method of renal replacement. However, …
Donor and recipient genetic interplay influences kidney transplant outcome but our knowledge …

The kidney as a determinant of genetic hypertension: evidence from renal transplantation studies

R Rettig, O Grisk - Hypertension, 2005 - Am Heart Assoc
… in genetically normotensive recipients of an SHRSP kidney … native kidney was removed
(ie, 7 days after transplantation). … Hypertension in man with a kidney transplant: role of familial …

Which genetic determinants should be considered for tacrolimus dose optimization in kidney transplantation? A combined analysis of genes affecting the CYP3A locus

H Bruckmueller, AN Werk, L Renders… - Therapeutic drug …, 2015 - journals.lww.com
… A total of 223 stable white kidney transplanted patients was included in this study. Subjects
were recruited from the Department of Nephrology and Hypertension, University Hospital …

Genetic determinants of delayed graft function after kidney transplantation.

SDS Peter, CJ Imber, DC Jones, SV Fuggle… - …, 2002 - journals.lww.com
… hypothesized that genetic variation in determinants of … transplants with over 24 hr of cold
ischemia and the subsequent requirement for hemodialysis in the first week after transplantation

[HTML][HTML] Tacrolimus troughs and genetic determinants of metabolism in kidney transplant recipients: A comparison of four ancestry groups

ME Mohamed, DP Schladt, W Guan, B Wu… - … of Transplantation, 2019 - Elsevier
… , multicenter study from which 2595 kidney transplant recipients of European, … genetic
determinants of metabolism. We studied the well-known variants and conducted a CYP3A4/5 gene-…

Genetic factors in pathogenesis of diabetes mellitus after kidney transplantation

M Tarnowski, S Słuczanowska-Głabowska… - … and Clinical Risk …, 2017 - Taylor & Francis
genetic factors have been considered important in PTDM development. The commonly
evaluated genetic determinants include genes … evaluated genetic determinants include genes

The genetics of kidney transplantation

N Pallet, E Thervet - Human genetics, 2012 - Springer
… are highly polymorphic, they are the most important genetic determinant of AR occurrence.
Notably, HLA matching based on antigenic characterization is used to predict alloimmunity …

Genetic and clinical determinants of early, acute calcineurin inhibitor-related nephrotoxicity: results from a kidney transplant consortium

PA Jacobson, D Schladt, A Israni, WS Oetting… - …, 2012 - journals.lww.com
… over time while on a CNI, or kidney biopsy suggestive of CNI toxicity has been previously
explored after kidney transplantation. These studies provide conflicting conclusions likely due …

[PDF][PDF] Genetics and epigenetics of chronic allograft dysfunction in kidney transplants

SZ Vahed, N Samadi, E Mostafidi… - … journal of kidney …, 2016 - researchgate.net
… Male sex is an independent prognostic factor for poor kidney transplant survival in addition
to acute rejection and delayed function. Better long-term prognosis in women may be …

[HTML][HTML] Transplantation genetics: current status and prospects

B Almoguera, A Shaked, BJ Keating - American Journal of Transplantation, 2014 - Elsevier
… non-HLA genetic determinants of clinical outcomes following organ transplantation have yet
… to hematopoietic stem cell transplantation (HSCT) and living kidney transplants. Therefore, …