… is a powerful tool for studying cellular and genetic processes in deep mammalian tissues. …
ideally suited as PA genetic reporters in more strongly attenuating mammalian tissues. This is …

… of expression of these reporter proteins (enzymes) usually require tissue samples; therefore,
… interactions in living subjects using reporter genes: the modified mammalian 2-hybrid, the …

… and to tissue sites of luciferase expression in vivo. Furthermore, we report noninvasive
monitoring of gene expression in living mammals from both superficial and deep tissue sites of ex…

… activity in mammalian cells can also be detected. GFPs have been widely used for
noninvasive monitoring of gene expression in living tissues, specifically with the advent of GFP …

… in small mammalian animal models. This review article examines the reporter gene strategies
… tissue. As cells progress down a specific developmental path, they undergo differential …

… The light spectrum of blue, green, and yellow can be easily absorbed by mammalian tissue;
… disturbed by the autofluorescence of endogenous tissue, resulting in substantial background …

… luciferase as a genetic reporter system for both Drosophila and mammalian adherent cells.
… from a gene of interest can be fused to the coding sequence of an unrelated gene whose …

… of tissues on BLI and the currently available reporter genes… genes encoding bioluminescent
reporters, the optical properties of tissues will have the same impact on fluorescent reporters …

… the desired tissue, expression of the reporter gene can be … to monitor reporter gene expression
include: (i) tissue biopsy … (a) The reporter gene should be present in mammalian cells, but …

… Ultrasound penetrates tissues, and cellular reporters that respond to ultrasound have been
… , we introduce mammalian acoustic reporter genes. Starting with a gene cluster derived from …