A novel genomic signature with translational significance for human idiopathic pulmonary fibrosis

Y Bauer, J Tedrow, S de Bernard… - American journal of …, 2015 - atsjournals.org
… However, this gene signature classified some of the control patients as IPF (6 from 108), …
To identify the minimal set of genes from the bleomycin-induced animal gene signature at Day 7 …

Heterogeneous gene expression signatures correspond to distinct lung pathologies and biomarkers of disease severity in idiopathic pulmonary fibrosis

DJ DePianto, S Chandriani, AR Abbas, G Jia… - Thorax, 2015 - thorax.bmj.com
gene signature score in control and idiopathic pulmonary … The bronchiolar signature is
similar to a set of genes reported … with concomitant pulmonary fibrosis and pulmonary artery …

[HTML][HTML] Identification of genetic signature associated with aging in pulmonary fibrosis

Y Lu, J Chen, S Wang, Z Tian, Y Fan, M Wang… - Frontiers in …, 2021 - frontiersin.org
… into the impact of aging on pulmonary fibrosis. We also identified four aging-associated
core genes (Slc2a3, Fga, Hp, and Thbs1) related to the development of pulmonary fibrosis. …

Identification of common signatures in idiopathic pulmonary fibrosis and lung cancer using gene expression modeling

D Leng, J Yi, M Xiang, H Zhao, Y Zhang - BMC cancer, 2020 - Springer
… identify gene signatures for lung disorders, the gene expression profiles of IPF and NSCLC
were compared with those of healthy controls individually, and 79 common signature genes

[HTML][HTML] Investigation of a hypoxia-immune-related microenvironment gene signature and prediction model for idiopathic pulmonary fibrosis

X Li, H Cai, Y Cai, Q Zhang, Y Ding… - Frontiers in …, 2021 - frontiersin.org
Background There is growing evidence found that the role of hypoxia and immune status in
idiopathic pulmonary fibrosis (IPF). However, there are few studies about the role of hypoxia …

… of a novel gene signature for predicting the prognosis of idiopathic pulmonary fibrosis based on three epithelial-mesenchymal transition and immune-related genes

J Zheng, H Dong, T Zhang, J Ning, Y Xu, C Cai - Frontiers in Genetics, 2022 - frontiersin.org
… -related genes. Cox and least absolute shrinkage and selection operator (LASSO) regression
analyses were used to screen prognostic genes and establish a gene signature. Gene Set …

Genetics and genomics of pulmonary fibrosis: charting the molecular landscape and shaping precision medicine

A Adegunsoye, JA Kropski, J Behr… - American Journal of …, 2024 - atsjournals.org
… Institutes of Health, Pulmonary Fibrosis Foundation and Chest … to the early diagnosis and
treatment of pulmonary fibrosis. … with a focus on the genetics of pulmonary fibrosis (dark blue). …

Biomarkers in idiopathic pulmonary fibrosis

F Drakopanagiotakis, L Wujak, M Wygrecka, P Markart - Matrix Biology, 2018 - Elsevier
pulmonary fibrosis (IPF) is a chronic, debilitating, fibrotic lung … , genetic variants of TOLLIP,
MUC5B, and other genes are … may identify comprehensive biomarker signatures in IPF patients…

Identification of the shared gene signatures between pulmonary fibrosis and pulmonary hypertension using bioinformatics analysis

H Zhao, L Wang, Y Yan, QH Zhao, J He… - Frontiers in …, 2023 - frontiersin.org
… PH is often accompanied by pulmonary fibrosis (PF). In idiopathic pulmonary fibrosis (IPF),
8%–… 2 depletion in idiopathic pulmonary fibrosis and Group III pulmonary hypertension. Am J …

Gene expression profiling in the lungs of patients with pulmonary hypertension associated with pulmonary fibrosis

M Mura, M Anraku, Z Yun, K McRae, M Liu, TK Waddell… - Chest, 2012 - Elsevier
… if different gene expression signatures in PF could be determined based on pulmonary
arterial … The 222-genes signature was interrogated in the intermediate PH group and in the …