Pharmacogenetics of migraine: genetic variants and their potential role in migraine therapy
… on genetic variants showing association with migraine. Table … outcomes for variants found
in migraine candidate genes. We … the genes according to their functional role in migraine as a …
in migraine candidate genes. We … the genes according to their functional role in migraine as a …
The impact of genetic factors on the response to migraine therapy
D Tsirelis, A Tsekouras, P Stamati… - Reviews in the …, 2024 - degruyter.com
… studies investigating the impact of genetic factors on migraine therapy outcome. Overall, 23
… genetic variants investigated. Divergent genes were assessed for each category of migraine …
… genetic variants investigated. Divergent genes were assessed for each category of migraine …
Pharmacogenetic considerations for migraine therapies
M Capi, G Gentile, L Lionetto, G Salerno… - Expert Opinion on …, 2018 - Taylor & Francis
… efficacy, will lead to identify new pharmacological targets and new individual therapies. The
description of genetic variants involved in migraine susceptibility may aid in the diagnosis of …
description of genetic variants involved in migraine susceptibility may aid in the diagnosis of …
[HTML][HTML] Advances in genetics of migraine
HG Sutherland, CL Albury, LR Griffiths - The journal of headache and pain, 2019 - Springer
… knockdown of Drosophila phospholipase C beta (PLCβ, which is involved in cardiovascular
and neuronal signalling), or genetic variants affecting the receptors that gate intracellular …
and neuronal signalling), or genetic variants affecting the receptors that gate intracellular …
A pharmacogenomic evaluation of migraine therapy
… of genetic variation within hormonal genes and their potential role in migraine etiology prompted
… receptor (AR) gene and an Alu indel within intron 7 of the progesterone receptor (PGR) …
… receptor (AR) gene and an Alu indel within intron 7 of the progesterone receptor (PGR) …
Gene polymorphisms involved in triptans pharmacokinetics and pharmacodynamics in migraine therapy
… and G861C 5HT1B gene variants upon sumatriptan therapy response was conduced by
MaassenVanDenBrink and colleagues in 1998 Citation[34] in 40 unrelated migraine patients (…
MaassenVanDenBrink and colleagues in 1998 Citation[34] in 40 unrelated migraine patients (…
Migraine pathways and the identification of novel therapeutic targets
I Rainero, F Roveta, A Vacca, C Noviello… - … on Therapeutic …, 2020 - Taylor & Francis
… migraine, candidate gene association studies showed that more than 200 genetic variants in
approximately 100 different genes … related genes, are significantly associated with migraine …
approximately 100 different genes … related genes, are significantly associated with migraine …
[HTML][HTML] Genetics, pathophysiology, diagnosis, treatment, management, and prevention of migraine
… Therapies for treating migraine have been tailored to modulate serotonin receptors. The
modulation is directed toward amplifying the serotonin signal, leading to pain relief via …
modulation is directed toward amplifying the serotonin signal, leading to pain relief via …
[HTML][HTML] Role of CGRP pathway polymorphisms in migraine: a systematic review and impact on CGRP mAbs migraine therapy
D Scuteri, MT Corasaniti, P Tonin, P Nicotera… - The journal of headache …, 2021 - Springer
… related peptide (CGRP), the present systematic review aims at identifying genetic variants
… clinical features and the course of disease and the responsiveness of patients to therapy. …
… clinical features and the course of disease and the responsiveness of patients to therapy. …
Genetic variants related to successful migraine prophylaxis with verapamil
FM Cutrer, AM Moyer, EJ Atkinson… - Molecular Genetics …, 2021 - Wiley Online Library
… with verapamil who showed the full range of possible responses to further assess genetic
predisposition to therapeutic responsiveness, while also investigating the role of metabolism …
predisposition to therapeutic responsiveness, while also investigating the role of metabolism …
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