… can actually increase the risk of gout in dominant model (… gout risk. Our results, combined
with those from previous studies, suggest that genetic variation in ABCG2 may influence gout …

… This review focuses on recent insights into these common genetic variants that contribute
to the development of gout, and their potential interaction with environmental risk factors. …

… risk of gout is controlled by inherited genetic variants, environmental exposures, gene–environment
interactions and intrinsic risk … the risk of gout, and there are documented gene–…

… by genetic variants is small and their clinical utility for gout risk … common genetic variants,
serum uric acid levels and gout as well as the role of these variants in hyperuricaemia and gout …

… [17] and to test genetic variants influencing inflammasome function for association with gout
in other population groups. Eleven functional variants were tested in eight genes involved in …

… Our results suggested that the Q141K variant results in increased gout risk in dominant,
recessive, and co-dominant models, and in subgroup analyses, Q126X also increased gout risk …

… The risk variants at each gene approximately double the risk for … As described later,
genetic variants in these genes have been associated with serum urate levels and gout. …

… In this case–control study, we identified 12 previously reported gout risk loci identified
through GWAS in European populations. Four susceptibility locis from chromosomes 4(…

… mitochondrial variation and/or dysfunction may be a risk factor for gout. We therefore tested
for association of mitochondrial genetic variation and mitochondrial copy number with gout in …

… of gout in both ancestral groups. … size on gout is seen [4], it is logical to expect that genetic
variants with a similar effect on serum urate should have a similar effect on the risk of gout. …