Host-Induced genome instability rapidly generates phenotypic variation across Candida albicans strains and ploidy states

AC Smith, MA Hickman - Msphere, 2020 - Am Soc Microbiol
… induces genome instability, but the magnitude depends on C. albicans genetic background.
… backgrounds, we were able to compare strain differences in genome stability both in vitro …

To Repeat or Not to Repeat: Repetitive Sequences Regulate Genome Stability in Candida albicans

MJ Dunn, MZ Anderson - Genes, 2019 - mdpi.com
albicans subtelomeres in the genome reference strain SC5314 based on the above definition
from the Candida Genome Database [60], but most genes remain largely uncharacterized (…

[PDF][PDF] Genetic instability of Candida albicans

E Rustchenko, F Sherman - MYCOLOGY SERIES, 2002 - ndl.ethernet.edu.et
… The subject of this chapter will be genetic instability based on mutational events, in contrast
to … the unique karyotype of each C. albicans strain creates a unique genomic condition (47; …

An evaluation of the role of LIG4 in genomic instability and adaptive mutagenesis in Candida albicans

E Andaluz, T Ciudad, G Larriba - FEMS yeast research, 2002 - academic.oup.com
albicans strains used in this study are listed in Table 1. They were routinely grown in YEPD
(… deletion of LIG4 on the genome stability of C. albicans, by comparing the electrokaryotypes …

Chromosome instability and unusual features of some widely used strains of Candida albicans

A Ahmad, MA Kabir, A Kravets, E Andaluz, G Larriba… - Yeast, 2008 - Wiley Online Library
… ChR instability in two major strains of the lineage, SC5314 and CAI4, we were concerned
about ChR stability … We asked whether the strain BWP17 has intolerance to the loss of genetic

Chromosome instability in Candida albicans

E Rustchenko - FEMS yeast research, 2007 - academic.oup.com
Candida albicans maintains genetic diversity by random chromosome alterations, and this
… from strain 3153A or from its unstable derivative 300. Indicated are five random colonies of …

Role of DNA Mismatch Repair and Double-Strand Break Repair in Genome Stability and Antifungal Drug Resistance in Candida albicans

M Legrand, CL Chan, PA Jauert, DT Kirkpatrick - Eukaryotic cell, 2007 - Am Soc Microbiol
… We observed an increase in genome instability in mre11Δ/… to an increase in genome
instability, while drug resistance … The yeast strains used in this study are described in Table 1. …

Comparative genome hybridization reveals widespread aneuploidy in Candida albicans laboratory strains

A Selmecki, S Bergmann, J Berman - Molecular microbiology, 2005 - Wiley Online Library
albicans strains. Furthermore, they highlight the high level of genome instability in C.
albicans laboratory strains exposed to the stress of transformation and counterselection on 5-fluoro-…

The Magnitude of Candida albicans Stress-Induced Genome Instability Results from an Interaction Between Ploidy and Antifungal Drugs

O Avramovska, MA Hickman - G3: Genes, Genomes, Genetics, 2019 - academic.oup.com
Yeast strains and media The strains used in this study are listed in Table S1. MH297 was
constructed by … All strains were stored as glycerol stocks at -80 and maintained on YPD (1% …

The contribution of the S-phase checkpoint genes MEC1 and SGS1 to genome stability maintenance in Candida albicans

M Legrand, CL Chan, PA Jauert… - Fungal Genetics and …, 2011 - Elsevier
… are characterized by an increase in genome instability. … Our data constrain the models
linking genome instability and … The yeast strains used in this study are described in Table 1. …