Genome‐level and biochemical diversity of the acyl‐activating enzyme superfamily in plants
… The diversity of AAE gene content likely arose due to large-scale and smaller-scale … of
genomes over evolutionary time, resulting in duplications of many genes in all gene families, …
genomes over evolutionary time, resulting in duplications of many genes in all gene families, …
Depiction of carbohydrate-active enzyme diversity in Caldicellulosiruptor sp. F32 at the genome level reveals insights into distinct polysaccharide degradation features
… of the carbohydrate-active enzyme (CAZyme) in the genome of Caldicellulosiruptor sp. F32,
… A thermostable β-glucosidase BlgA synergistically facilitated the enzymatic degradation of …
… A thermostable β-glucosidase BlgA synergistically facilitated the enzymatic degradation of …
… genomics of the HAD superfamily: understanding the structural adaptations and catalytic diversity in a superfamily of phosphoesterases and allied enzymes
AM Burroughs, KN Allen, D Dunaway-Mariano… - Journal of molecular …, 2006 - Elsevier
… enzyme haloacid dehalogenase, 9 includes enzymes catalyzing carbon or phosphoryl group
transfer reactions on a diverse … The majority of the enzymes in this superfamily are involved …
transfer reactions on a diverse … The majority of the enzymes in this superfamily are involved …
Functional genomics and enzyme evolution
MY Galperin, EV Koonin - Genetica, 1999 - Springer
… Most importantly, we can expect to obtain a good coverage of the diversity of life, as
complete genomes of many phylogenetically divergent bacteria, several crenarchaea and …
complete genomes of many phylogenetically divergent bacteria, several crenarchaea and …
Revealing the hidden functional diversity of an enzyme family
K Bastard, AAT Smith, C Vergne-Vaxelaire… - Nature chemical …, 2014 - nature.com
… This enzymatic activity diversity is also reflected by the various genomic contexts that we
observed. One of them (BKACE_274), found in Burkholderia graminis C4D1M, presents a …
observed. One of them (BKACE_274), found in Burkholderia graminis C4D1M, presents a …
Evolution of digestive enzyme genes associated with dietary diversity of crabs
Z Wang, D Tang, H Guo, C Shen, L Wu, Y Luo - Genetica, 2020 - Springer
… diverse feeding strategies. The primary objective of this study was to investigate 10 digestive
enzyme … S2, and the length of each gene is in Table S3. The sequences of the 10 digestive …
enzyme … S2, and the length of each gene is in Table S3. The sequences of the 10 digestive …
Exploration of enzyme diversity by integrating bioinformatics with expression analysis and biochemical characterization
P Vanacek, E Sebestova, P Babkova, S Bidmanova… - Acs …, 2018 - ACS Publications
… enormous wealth of genomic sequences available in public databases can be efficiently
explored by in silico mapping of proteins structural and functional diversity within protein families…
explored by in silico mapping of proteins structural and functional diversity within protein families…
Evolution of enzyme superfamilies
ME Glasner, JA Gerlt, PC Babbitt - Current opinion in chemical biology, 2006 - Elsevier
… of mechanistically diverse superfamilies in the … genome annotation, function prediction and
protein engineering. In this review, we discuss evolutionary themes in mechanistically diverse …
protein engineering. In this review, we discuss evolutionary themes in mechanistically diverse …
Evolution of genome–phenome diversity under environmental stress
E Nevo - Proceedings of the National Academy of Sciences, 2001 - National Acad Sciences
… repeats or SSR), single nucleotide polymorphism (SNP) and sequence comparisons—are
several-fold higher than enzymatic diversity. The elucidation and significance of molecular …
several-fold higher than enzymatic diversity. The elucidation and significance of molecular …
Evolution of enzyme superfamilies: comprehensive exploration of sequence–function relationships
… functional diversity and evolutionary relationships within enzyme … of enzyme evolution and
superfamily functional diversity. We … to which enzymes belong, ie, if the gene is localized to an …
superfamily functional diversity. We … to which enzymes belong, ie, if the gene is localized to an …
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