… leprae genome sequence would have helped focus this work considerably, since only one
of these five M. tuberculosis genes has a functional orthologue, with ML2387 corresponding …

… is a paucity of targets that meet such ideal cancer target criteria. Recent … targets presented
as peptides in the context of human leukocyte antigen (peptide–human leukocyte antigen …

… genome sequence of C. pseudotuberculosis biovar equi strain 258, isolated from a horse
with ulcerative lymphangitis. The genome … IV, we screened for antigenic targets harbored by …

… As one of the major problems with meningococcal antigens is sequence variability, the …
This analysis yielded a handful of antigens, which were both conserved in sequence and …

… the native target protein. Antigens are preferably selected on parts of the protein shared by
all splice variants of the target gene, to cover all proteins encoded by the target gene with the …

… genes encoding new antigens or drug targets. We searched for genomic regions with …
balancing selection) that may harbor genes encoding antigens. Indeed, approximately 40% of the …

… the non-epitope encoding sequences of the same Mtb antigens [136] (in this work 491
experimentally verified peptides were studied covering 78 Mtb antigens). This discussion impacts …

… the seven proteins displaying antigenic responses are promising targets for further studies
… for designation as an EBA-specific antigen in the target bovine species. In silico analysis of …

… target pathogens. Cell-mediated immunity, in contrast, is based upon the binding of short
sequences of antigen … diversity, illustrative of the reassortment of the genome segments among …

… To further characterize these target antigens as vaccine candidates, we studied surface
expression by immunoblotting outer membrane preparations and we studied accessibility of …