The developmental epigenomics toolbox: ChIP-seq and MethylCap-seq profiling of early zebrafish embryos

O Bogdanović, A Fernández-Miñán, JJ Tena… - Methods, 2013 - Elsevier
… -regulated DNA methylation remodeling … DNA methylation studies of early zebrafish
development rendering this method highly suitable for the global assessment of DNA methylation in …

[HTML][HTML] High resolution imaging of DNA methylation dynamics using a zebrafish reporter

R Zhang, L Liu, Y Yao, F Fei, F Wang, Q Yang, Y Gui… - Scientific Reports, 2017 - nature.com
… of DNA methylation, we generated a transgenic zebrafish reporter of DNA methylation (…
of DNA methylation, and time-lapse imaging at the blastula stage showed that the level of …

[HTML][HTML] Developmental accumulation of gene body and transposon non-CpG methylation in the zebrafish brain

SE Ross, D Hesselson, O Bogdanovic - Frontiers in Cell and …, 2021 - frontiersin.org
DNA methylation predominantly occurs at CG dinucleotides in vertebrate genomes; however,
non-CG methylation (mCH) is also detectable in vertebrate tissues, most notably in the …

The specific alteration of histone methylation profiles by DZNep during early zebrafish development

O Østrup, AH Reiner, P Aleström, P Collas - Biochimica et Biophysica Acta …, 2014 - Elsevier
… We first investigated the effect of DZNep on early zebrafish development by growing
dechorionated 1–2 cell stage embryos in increasing DZNep concentrations for up to 120 h post-…

DNA methylation and histone modifications are essential for regulation of stem cell formation and differentiation in zebrafish development

AD Marchione, Z Thompson… - … in functional genomics, 2021 - academic.oup.com
… , including methylation and acetylation of specific lysine (K) residues, are established on
histones [3]. Genomes undergo global methylation changes to stabilize DNA methylation levels …

Packaging development: how chromatin controls transcription in zebrafish embryogenesis

JA Horsfield - Biochemical Society Transactions, 2019 - portlandpress.com
… transcriptional programmes during early zebrafish development, patterning and … DNA
methylation patterns of the two parental genomes by passively deterring DNA methylation

[HTML][HTML] UHRF1 regulation of Dnmt1 is required for pre-gastrula zebrafish development

B Kent, E Magnani, MJ Walsh, KC Sadler - Developmental biology, 2016 - Elsevier
… largely mediate maintenance DNA methylation and Uhrf1 is … modifiers regulate early zebrafish
development and … , we conclude that bulk DNA methylation is not the primary mechanism. …

Dynamics of DNA hydroxymethylation in zebrafish

JH Kamstra, M Løken, P Aleström, J Legler - Zebrafish, 2015 - liebertpub.com
… hmC is not present during early zebrafish development, 16,21 … Even though the DNA
methylation level in the zebrafish … maternal genome leads to, our results show a lower methylation

Molecular evolution of zebrafish dnmt3 genes and thermal plasticity of their expression during embryonic development

C Campos, LMP Valente, JMO Fernandes - Gene, 2012 - Elsevier
… In mammals, proper patterns of DNA methylation are essential not only for … DNA methylation
reprogramming has been investigated. Significant differences in genome DNA methylation

[HTML][HTML] Ionising radiation induces promoter DNA hypomethylation and perturbs transcriptional activity of genes involved in morphogenesis during gastrulation in …

S Murat El Houdigui, C Adam-Guillermin… - International Journal of …, 2020 - mdpi.com
… To assess whether IR can modify epigenetic marks and thereby modulate transcriptional
activity, we analysed DNA methylation at the whole genome scale using WGBS on shield stage …