Interrelationships amongst radiation-induced genomic instability, bystander effects, and the adaptive response

MA Kadhim, SR Moore, EH Goodwin - Mutation Research/Fundamental …, 2004 - Elsevier
… These responses include now familiar, but still poorly … effects, genomic instability, and
adaptive responses. All three … to low doses; the adaptive response is particularly relevant when …

Bystander effects, genomic instability, adaptive response, and cancer risk assessment for radiation and chemical exposures

RJ Preston - Toxicology and Applied Pharmacology, 2005 - Elsevier
… Similarly, induced genomic instability can alter the concept of total response to an exposure.
… the etiology of these cellular responses. The adaptive response appears to be inducible at …

A biological-based model that links genomic instability, bystander effects, and adaptive response

BR Scott - … Research/Fundamental and Molecular Mechanisms of …, 2004 - Elsevier
… This paper links genomic instability, bystander effects, and adaptive response in … that can
be associated with varying degrees of genomic instability. Cells with persistent problematic …

Systemic DNA damage responses: organismal adaptations to genome instability

MA Ermolaeva, B Schumacher - Trends in Genetics, 2014 - cell.com
… of the immune response in mammals makes it worthwhile to consider more ancestral model
systems to understand how distinct tissues interact in the presence of genome instability. …

Bystander effects, adaptive response and genomic instability induced by prenatal irradiation

C Streffer - … Research/Fundamental and Molecular Mechanisms of …, 2004 - Elsevier
adaptive response could lead to reduced levels of effect, while the induction of genomic
instability or … to induce bystander effects, adaptive responses and genomic instability, it is of high …

Molecular mechanisms of low dose ionizing radiation-induced hormesis, adaptive responses, radioresistance, bystander effects, and genomic instability

FR Tang, WK Loke - International journal of radiation biology, 2015 - Taylor & Francis
responses may have different signal transduction pathways. On the other hand, LDIR-induced
different responses … hormesis, adaptive response, radioresistance and genomic instability. …

Destructive cycles: the role of genomic instability and adaptation in carcinogenesis

BL Schneider, M Kulesz-Martin - Carcinogenesis, 2004 - academic.oup.com
… However, there is growing evidence that genomic instability … how the role of genomic instability
and aneuploidy are changing … that behave as a complex adaptive system governed by the …

[HTML][HTML] Genomic instability, inflammatory signaling and response to cancer immunotherapy

M Chen, R Linstra, MATM van Vugt - … et Biophysica Acta (BBA)-Reviews on …, 2022 - Elsevier
… induced by various sources of genomic instability, adaptation mechanisms that suppress …
In contrast to mutation-driven adaptive immune responses, cancer-associated genomic

Targeted and nontargeted effects of low-dose ionizing radiation on delayed genomic instability in human cells

L Huang, PM Kim, JA Nickoloff, WF Morgan - Cancer research, 2007 - AACR
adaptive response for genome instability described above, we were also interested in
whether medium transferred from irradiated RKO36 cells would enhance genome instability as …

IR-inducible clusterin gene expression: a protein with potential roles in ionizing radiation-induced adaptive responses, genomic instability, and bystander effects

D Klokov, T Criswell, KS Leskov, S Araki, L Mayo… - Mutation Research …, 2004 - Elsevier
… interest: bystander effects, adaptive responses and genomic instability. Although the three
… radiation-induced genomic instability, bystander effects and adaptive responses. Based on …