Genomic landscape of young ATLL patients identifies frequent targetable CD28 fusions

N Yoshida, K Shigemori, N Donaldson… - Blood, The Journal …, 2020 - ashpublications.org
… Thus, we hypothesized that ATLL in younger patients will … genes 11 in ATLL samples from
8 Japanese patients <50 years … The previous study 2 included 9 ATLL patients <50 years old …

Whole-genome landscape of adult T-cell leukemia/lymphoma

Y Kogure, T Kameda, J Koya… - Blood, The Journal …, 2022 - ashpublications.org
… We performed WGS of 150 ATL patients to reveal the overarching landscape of genomic
Patients and materials A total of 150 patients with ATL were enrolled in this study, of which 11 …

Clinical applications of genomic alterations in ATLL: predictive markers and therapeutic targets

N Yoshida, H Miyoshi, K Ohshima - Cancers, 2021 - mdpi.com
… Recent comprehensive genomic analyses have revealed the genomic landscape. One of …
ATLL patients in Caribbean islands tend to be younger than those in Japan and the landscape

North American ATLL has a distinct mutational and transcriptional profile and responds to epigenetic therapies

UA Shah, EY Chung, O Giricz… - Blood, The Journal …, 2018 - ashpublications.org
… American ATLL has a distinct genomic landscapelandscape and transcriptomics of North
American ATLL. We report that, compared with Japanese ATLL patients, North American ATLL

Molecular and genomic landscape of peripheral T-cell lymphoma

J Iqbal, C Amador, TW McKeithan, WC Chan - T-Cell and NK-Cell …, 2019 - Springer
… Another study of uncultured lymphocytes from ATLL patients showed increased expression
… in the treatment of ATLL. We also identified a unique signature for ATLL with many of the …

[HTML][HTML] Genomic Landscape of Young ATLL Patients Identifies Frequent Targetable CD28 Fusions

N Yoshida, K Shigemori, SY Ng, A Nirmal… - Blood, 2019 - Elsevier
ATLL patients in Japan present at age <50. Here, we hypothesized that ATLL in younger
patients … Here, we hypothesized that ATLL in younger patients will have distinct genetic …

Clinical application of genomic aberrations in adult T-cell leukemia/lymphoma

K Kataoka, J Koya - Journal of clinical and experimental …, 2020 - jstage.jst.go.jp
… North American patients than in Japanese ATL patients, suggesting … have delineated the
entire landscape of genetic alterations and … North American ATLL has a distinct mutational and …

Comprehensive genomic analysis identifying heterogeneity in peripheral T‐cell lymphoma

N Yoshida, K Yamada, K Ohshima - Cancer Science, 2021 - Wiley Online Library
genomic alterations of ATLL in North America 11 identified a distinct genomic landscape with
… We speculated that ATLL in younger patients would exhibit distinct genetic alterations and, …

Genomics of LGL leukemia and select other rare leukemia/lymphomas

KB Moosic, U Paila, KC Olson, K Dziewulska… - Best Practice & …, 2019 - Elsevier
… to treatment in all patients with Y640F mutations who … A genomic landscape study of 40 cases
of CTCL identified … Potentially mediated by these epigenetic factors, ATLL genomes (40%) …

[HTML][HTML] Notable Patterns in the Genomic Landscape of Adult T-Cell Leukemia/Lymphoma Encountered in HTLV-1 Endemic Western World Regions

AA Gru, C Snowden, E Williams, C Barrionuevo… - Blood, 2021 - Elsevier
genomic landscape of ATLL encountered in patients from South America and the Caribbean
resembles that of ATLL in Japanese patients. … previously implicated in ATLL that differ from …