Genomic landscape of young ATLL patients identifies frequent targetable CD28 fusions
N Yoshida, K Shigemori, N Donaldson… - Blood, The Journal …, 2020 - ashpublications.org
… Thus, we hypothesized that ATLL in younger patients will … genes 11 in ATLL samples from
8 Japanese patients <50 years … The previous study 2 included 9 ATLL patients <50 years old …
8 Japanese patients <50 years … The previous study 2 included 9 ATLL patients <50 years old …
Whole-genome landscape of adult T-cell leukemia/lymphoma
… We performed WGS of 150 ATL patients to reveal the overarching landscape of genomic …
Patients and materials A total of 150 patients with ATL were enrolled in this study, of which 11 …
Patients and materials A total of 150 patients with ATL were enrolled in this study, of which 11 …
Clinical applications of genomic alterations in ATLL: predictive markers and therapeutic targets
N Yoshida, H Miyoshi, K Ohshima - Cancers, 2021 - mdpi.com
… Recent comprehensive genomic analyses have revealed the genomic landscape. One of …
ATLL patients in Caribbean islands tend to be younger than those in Japan and the landscape …
ATLL patients in Caribbean islands tend to be younger than those in Japan and the landscape …
North American ATLL has a distinct mutational and transcriptional profile and responds to epigenetic therapies
… American ATLL has a distinct genomic landscape … landscape and transcriptomics of North
American ATLL. We report that, compared with Japanese ATLL patients, North American ATLL …
American ATLL. We report that, compared with Japanese ATLL patients, North American ATLL …
Molecular and genomic landscape of peripheral T-cell lymphoma
J Iqbal, C Amador, TW McKeithan, WC Chan - T-Cell and NK-Cell …, 2019 - Springer
… Another study of uncultured lymphocytes from ATLL patients showed increased expression
… in the treatment of ATLL. We also identified a unique signature for ATLL with many of the …
… in the treatment of ATLL. We also identified a unique signature for ATLL with many of the …
[HTML][HTML] Genomic Landscape of Young ATLL Patients Identifies Frequent Targetable CD28 Fusions
N Yoshida, K Shigemori, SY Ng, A Nirmal… - Blood, 2019 - Elsevier
… ATLL patients in Japan present at age <50. Here, we hypothesized that ATLL in younger
patients … Here, we hypothesized that ATLL in younger patients will have distinct genetic …
patients … Here, we hypothesized that ATLL in younger patients will have distinct genetic …
Clinical application of genomic aberrations in adult T-cell leukemia/lymphoma
… North American patients than in Japanese ATL patients, suggesting … have delineated the
entire landscape of genetic alterations and … North American ATLL has a distinct mutational and …
entire landscape of genetic alterations and … North American ATLL has a distinct mutational and …
Comprehensive genomic analysis identifying heterogeneity in peripheral T‐cell lymphoma
N Yoshida, K Yamada, K Ohshima - Cancer Science, 2021 - Wiley Online Library
… genomic alterations of ATLL in North America 11 identified a distinct genomic landscape with
… We speculated that ATLL in younger patients would exhibit distinct genetic alterations and, …
… We speculated that ATLL in younger patients would exhibit distinct genetic alterations and, …
Genomics of LGL leukemia and select other rare leukemia/lymphomas
… to treatment in all patients with Y640F mutations who … A genomic landscape study of 40 cases
of CTCL identified … Potentially mediated by these epigenetic factors, ATLL genomes (40%) …
of CTCL identified … Potentially mediated by these epigenetic factors, ATLL genomes (40%) …
[HTML][HTML] Notable Patterns in the Genomic Landscape of Adult T-Cell Leukemia/Lymphoma Encountered in HTLV-1 Endemic Western World Regions
AA Gru, C Snowden, E Williams, C Barrionuevo… - Blood, 2021 - Elsevier
… genomic landscape of ATLL encountered in patients from South America and the Caribbean
resembles that of ATLL in Japanese patients. … previously implicated in ATLL that differ from …
resembles that of ATLL in Japanese patients. … previously implicated in ATLL that differ from …