The genomic landscape of breast cancer and its interaction with host immunity

S Luen, B Virassamy, P Savas, R Salgado, S Loi - The Breast, 2016 - Elsevier
… between genomic alteration landscapes and host anti-tumour immunity are being explored.
This review article aims to summarise the genomic and driver landscape of breast cancer, …

The genomic landscape of breast cancer brain metastases: a systematic review

AJ Morgan, A Giannoudis, C Palmieri - The Lancet Oncology, 2021 - thelancet.com
… brain metastases from breast cancer have a distinct genomic landscape to that … breast
tumour. In this Review, we aim to review and evaluate genomic sequencing data for breast cancer

The genomic landscape of male breast cancers

S Piscuoglio, CKY Ng, MP Murray… - Clinical Cancer …, 2016 - AACR
… Purpose: Male breast cancer is rare, and its genomic landscape has yet to be fully … of males
with breast cancer is extrapolated from results in females with breast cancer. We sought to …

[HTML][HTML] The genomic landscape of endocrine-resistant advanced breast cancers

P Razavi, MT Chang, G Xu, C Bandlamudi, DS Ross… - Cancer cell, 2018 - cell.com
… We integrated the genomic sequencing of 1,918 breast cancers, including 1,501 hormone
receptor-positive tumors, with detailed clinical information and treatment outcomes. In 692 …

[HTML][HTML] The genomic landscape of metastatic breast cancer: Insights from 11,000 tumors

J Rinaldi, ES Sokol, RJ Hartmaier, SE Trabucco… - PLoS …, 2020 - journals.plos.org
… These constitute a substantial expansion of genomic profiling for rare breast cancers (Fig
1E). The genomic landscapes of these rare subtypes differ substantially from IDC and ILC, and …

The genomic landscape of metastatic breast cancer highlights changes in mutation and signature frequencies

L Angus, M Smid, SM Wilting, J van Riet, A Van Hoeck… - Nature …, 2019 - nature.com
cancer, tumor mutational burden doubles, the relative … genes increases in metastatic breast
cancer. Significant associations with … breast cancer and identifies clinically useful genomic

[HTML][HTML] The genomic landscape of lobular breast cancer

AE McCart Reed, S Foong, JR Kutasovic, K Nones… - Cancers, 2021 - mdpi.com
breast cancer, there are several large studies that provide detailed analysis of the genomics
… Indeed, applying WGS, [46] showed that metastatic breast cancers have a higher tumour …

Genomic characterization of metastatic breast cancers

F Bertucci, CKY Ng, A Patsouris, N Droin, S Piscuoglio… - Nature, 2019 - nature.com
… In order to decipher the genomic landscape of metastatic breast cancer (mBC), we sequenced
617 tumour samples from patients with mBC using whole-exome sequencing. For each …

[HTML][HTML] Functional genomic landscape of human breast cancer drivers, vulnerabilities, and resistance

R Marcotte, A Sayad, KR Brown, F Sanchez-Garcia… - Cell, 2016 - cell.com
… type and none represented the diversity of neoplasms such as breast cancer. Here, we
report the results of genome-wide shRNA screens of >75 breast cancer lines with genomic, …

The genomic landscape of mucinous breast cancer

F Pareja, JY Lee, DN Brown… - … the National Cancer …, 2019 - academic.oup.com
… Mucinous carcinoma of the breast (MCB) is a rare histologic form of … breast cancer (BC)
characterized by tumor cells floating in lakes of mucin. We assessed the genomic landscape of …