Genotoxic effects of fluoride: a controversial issue
Y Li, AJ Dunipace, GK Stookey - Mutation Research/Reviews in Genetic …, 1988 - Elsevier
… Attempts to induce meiotic abnormalities in mouse oocytes in vivo with acute (500/~g NaF,
single iv) or chronic (250/~g NaF, sc for 16 days) fluoride exposure failed to produce …
single iv) or chronic (250/~g NaF, sc for 16 days) fluoride exposure failed to produce …
Putative mechanisms of genotoxicity induced by fluoride: a comprehensive review
DA Ribeiro, VQ Yujra, VHP da Silva… - … Science and Pollution …, 2017 - Springer
… By comparison, others have yet mentioned that fluoride exposure generates reactive
oxygen species (ROS) by SIRT1/autophagy induction through c-Jun N-terminal kinase (JNK) …
oxygen species (ROS) by SIRT1/autophagy induction through c-Jun N-terminal kinase (JNK) …
Genotoxic effect and rat hepatocyte death occurred after oxidative stress induction and antioxidant gene downregulation caused by long term fluoride exposure
FD Campos-Pereira, L Lopes-Aguiar… - Chemico-biological …, 2017 - Elsevier
… to investigate genotoxic potential of fluoride. The … genotoxic potential of fluoride but did not
confirm mitochondrial swelling nor an increase of positive TUNEL labelling induced by fluoride…
confirm mitochondrial swelling nor an increase of positive TUNEL labelling induced by fluoride…
Genotoxic evaluation of chronic fluoride exposure: sister-chromatid exchange study
Y Li, W Zhang, TW Noblitt, AJ Dunipace… - Mutation Research …, 1989 - Elsevier
… As part of a continuing investigation, this study was conducted to examine the genotoxic
effects of chronic exposure to sodium fluoride (NaF) in drinking water on the frequency of sister-…
effects of chronic exposure to sodium fluoride (NaF) in drinking water on the frequency of sister-…
Genotoxic evaluation of chronic fluoride exposure: micronucleus and sperm morphology studies
AJ Dunipace, W Zhang, TW Noblitt… - Journal of Dental …, 1989 - journals.sagepub.com
… The purpose of this study was to investigate the genotoxic effects of chronic fluoride exposure
on mammalian cells in vivo by use of the mouse bone-marrow micronucleus test and the …
on mammalian cells in vivo by use of the mouse bone-marrow micronucleus test and the …
Investigation of the genotoxic effects of fluoride on a bone tissue model
VP Volobaev, ES Serdyukova, EE Kalyuzhnaya… - Toxicological …, 2020 - Springer
… exert genotoxic effects on bone cells indirectly indicates the possible importance of fluoride
… hypothesis, an experimental assessment of the genotoxic effects of fluoride-ion exposure on …
… hypothesis, an experimental assessment of the genotoxic effects of fluoride-ion exposure on …
A review on fluoride induced organotoxicity and genotoxicity in mammals and zebrafish
A Dey Bhowmik, A Chattopadhyay - The nucleus, 2019 - Springer
… , chronic fluoride exposure beyond the permissible limit causes detrimental effect on soft …
Studies also indicate that fluoride induces significantly genotoxic effect both in vivo and in …
Studies also indicate that fluoride induces significantly genotoxic effect both in vivo and in …
Genotoxic effects of fluoride evaluated by sister-chromatid exchange
Y Li, NA Heerema, AJ Dunipace, GK Stookey - Mutation Research Letters, 1987 - Elsevier
… genotoxic potential of fluoride (in the form of sodium fluoride, … Fluoride analysis of the culture
medium demonstrated that it … indigenous fluoride, and the concentration of added fluoride …
medium demonstrated that it … indigenous fluoride, and the concentration of added fluoride …
Effects of long-term fluoride exposure are associated with oxidative biochemistry impairment and global proteomic modulation, but not genotoxicity, in parotid glands …
GHN Miranda, L Alencar de Oliveira Lima… - Plos one, 2022 - journals.plos.org
… Thus, this study aimed to investigate the effects of long-term exposure to F on the parotid
salivary gland of mice, from the analysis of oxidative, proteomic and genotoxic parameters. …
salivary gland of mice, from the analysis of oxidative, proteomic and genotoxic parameters. …
Lack of effect of prior treatment with fluoride on genotoxicity of two chemical agents in vitro
… ability of fluoride to modulate the genotoxic effects induced by the oxidative agent hydrogen
… Chinese hamster ovary cells were exposed in culture for 1 h at 37C to sodium fluoride at 7–…
… Chinese hamster ovary cells were exposed in culture for 1 h at 37C to sodium fluoride at 7–…
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