… Studies focusing on possible genotoxic effects of excess … Micronucleus test was applied to
investigate genotoxic potential of … Our results revealed the genotoxic potential of fluoride but …

… Although neither a single gene nor a single pathway will be … gene expression profiles
may be used to predict a genotoxic or … Improved cell thriving 13 11 Downregulation of genes …

… also downregulated by BaP treatment (this gene was not originally included in the panel of
significantly downregulated genes in microarray analysis). In the case of upregulated genes, …

… As these authors recognise this idea would need further research; in fact in our study
down-regulation was more predominant in the shorter time point where the cytotoxic effect was less …

… corresponding upregulation of inflammatory genes at the same … genes and pathways
commonly deregulated by genotoxic … genes exceeded the number of downregulated genes. …

… We observed significant downregulation of the XRCC3 and HSP70 genes with the Mix2
treatment compared to other treatment groups. Insufficient DNA repair mechanisms can cause …

… gene expression in murine cells after exposure to genotoxic … Among the genes identified in
this screen were several that … to genotoxic exposure that results in the down-regulation of both …

… no effect on transcript levels for any of the genes examined. Therefore, while transcripts for
genotoxic stress-response genes … play a role in the downregulation of stress-response genes. …

… In contrast, the expression of these genes with the highest concentration were downregulated,
… of Vz on gene transcription of an insect and confirm the potential genotoxicity of this …

… genotoxicity screening and identification of modes of action of carcinogens. Here, we investigated
whether gene … with up- and down-regulation levels set at 0.6 (implying a 1.5-fold up- or …