… IFN-γ drastically reduced the levels of VSV-neutralizing IgG. Our results suggest that the IFN-γ
… either an irrelevant antigen (LCMV-NP) or IFN-γ, together with UV-inactivated VSV, did not …

… Overactivity of the germinal center (GC) pathway resulting … identifed posttranscriptional
repression of interferon-γ (Ifng) … Ifng mRNA decay caused excessive IFN-γ signaling in T cells and …

… IFN and IFN-γ in lupus pathogenesis. Surprisingly, despite prominent effects of type 1 IFN
on B cell activation in vitro, a lack of B cell type 1 IFN … a marked expansion of IFN-γ–producing …

… In this study, we report that B cell–intrinsic IFN-γ receptor (IFN-γR) and STAT1 … IFN-γR and
STAT1 signaling control Spt-GC and Tfh cell formation by driving T-bet expression and IFN-γ …

The mechanisms responsible for degeneration of germinal centers (GC) and follicular dendritic
cell (FDC) networks during progression to AIDS remain elusive. Here, we show that CD4 …

… Other studies have also provided evidence for somatic mutation in germinal center cells
by isolating germinal center cells from dissociated lymphoid tissues on the basis of their …

… -21, IFN-γ, IL-… germinal center reactions that lead to pathogenic autoantibody formation.
Here we review recent discoveries into the roles of IL-21, IFN-γ, IL-6, and IL-17 in germinal center …

… Germinal centers (GC) primarily consist of B cells along with a small number of T cells (5
to 10%) and follicular dendritic cells (FDC) (51%). Although extensive Ag-driven B cell …

… IgD ± non-germinal center (non-GC) B cells. CD40 ligation and interferon (IFN)-γ exhibited
synergistic … Blockade of CD40 and/or IL-12 during T–B interaction significantly reduced IFN-γ …

… This study reveals Gal-3 as a key factor in the development of IFN-γ-mediated lupus-like …
serum IFN-γ and increased numbers of IFN-γ-producing cells in Gal-3 KO mice. Increased IFN-γ …