… We combined the GFAP promoter with EGFP and generated transgenic mice with the aim
to obtain an animal model that allows imaging of astrocytes in the living brain slice and, …

… from the human GFAP gene that previously was … promoter directs expression to astrocytes
in the CNS. In addition, the upregulation of GFAP gene activity that follows injury to the brain …

… in human and mouse brain and also in mouse bone marrow … the junction between the GFAP
promoter and a reporter gene … it in any GFAP promoter to be used in transgenic mice. Since …

… to express in certain brain regions, and for suppression of GFAP expression in neurons. Block
… -nLac transgene or to the endogenous mouse GFAP promoter could be detected by ChIP …

… the gfaABCnD-lacZ mice analyzed were founders. Brains from adult mice were stained for
24 … for GFAP expression in several brain regions is present in the 55 bp C 1.1 segment of the …

… In the developing brain, P-gal activity and GFAP appeared … 2 kb sequence of the GFAP
promoter used in the transgene … reactive gliosis in these transgenic mice. These transgenic lines …

… mouse bearing part of the gene promoter of the astrocytic maturation marker GFAP linked to
… suggest that neurons secrete brain region-specific soluble factors which induce GFAP gene …

… human GFAP promoter to drive Cre recombinase suggest that GFAP-… of oligodendrocytes
throughout brain and spinal cord. … brain, the GFAP promoter used to make our GFAP-Cre mice …

… 3:465–474, (1991)] have reported astrocyte specificity for GFAP promoters, we demonstrate
… % of total brain protein (7). However, we report here that both the human and mouse GFAP …

… a transgenic mouse brain tumor model where combined over-expression of PDGFB under
control of the GFAP promoter and lack of Trp53 results in development of brain tumors at high …