Increase of insulin secretion by ginsenoside Rh2 to lower plasma glucose in Wistar rats

WK Lee, ST Kao, IM Liu… - Clinical and Experimental …, 2006 - Wiley Online Library
… injection of 1.0 mg/kg ginsenoside Rh2. Thus, the effect of ginsenoside Rh2 on plasma
glucose and insulin concentrations were determined using blood samples collected 60 min after …

Mediation of β-endorphin by ginsenoside Rh2 to lower plasma glucose in streptozotocin-induced diabetic rats

DM Lai, YK Tu, IM Liu, PF Chen, JT Cheng - Planta medica, 2006 - thieme-connect.com
… of glucose transporter subtype 4 (GLUT 4) was observed in soleus muscle obtained from
STZ-diabetic rats treated with Rh2 … suggest that ginsenoside Rh2 may lower plasma glucose in …

Ginsenoside Rh2 is one of the active principles of Panax ginseng root to improve insulin sensitivity in fructose-rich chow-fed rats

WK Lee, ST Kao, IM Liu… - Hormone and metabolic …, 2007 - thieme-connect.com
… In the present study, an iv injection of ginsenoside Rh2 was found to decrease the plasma
glucose concentration of fructose-rich chow-fed rats in a dose-dependent manner, showing …

Antihyperglycemic effect of ginsenoside Rh2 by inducing islet β-cell regeneration in mice

Y Wang, H Wang, Y Liu, C Li, P Qi… - Hormone and Metabolic …, 2012 - thieme-connect.com
… In contrast, GS-Rh2-treated mice did not show fasting blood glucose levels that were
significantly >250 mg/dl after 5 days of treatment. No statistically significant difference in body …

Anti-diabetic Effects of Ginsenosides Rh2 and F1 in the Type 2 Diabetes Mellitus Mice Model

이승리 - 2013 - s-space.snu.ac.kr
… In conclusion, we demonstrate that the ginsenosides Rh2 and F1 have beneficial effects
in that they decrease blood glucose and HbA1c levels in the db/db mice model. It was …

[HTML][HTML] Ginsenoside Rb2: A review of pharmacokinetics and pharmacological effects

L Miao, Y Yang, Z Li, Z Fang, Y Zhang, C Han - Journal of Ginseng …, 2022 - Elsevier
… Rb2 at treatment with 25 μM enhanced glucose uptake and attenuated TNF-α-induced …
blood glucose level is a clinical syndrome with diabetes, and Rb2 has a positive effect on glucose

Ginsenoside Rh2 improves cardiac fibrosis via PPARδ–STAT3 signaling in type 1-like diabetic rats

SH Lo, CT Hsu, HS Niu, CS Niu, JT Cheng… - International journal of …, 2017 - mdpi.com
… In the present study, the plasma glucose level was substantially higher in the STZ-diabetic
rats than in the normal rats, indicating the success of diabetes model induction. The cardiac …

Liquid chromatography/mass spectrometric analysis of rat samples for in vivo metabolism and pharmacokinetic studies of ginsenoside Rh2

T Qian, Z Cai, RNS Wong… - Rapid Communications in …, 2005 - Wiley Online Library
glucose moiety, respectively. The ion at m/z 203 probably represents the sodium ion adduct
of the glucose … patterns were observed for the oxygenated metabolite of Rh2 (m2, Fig. 4(B)) …

Pharmacokinetics of Ginsenoside Rh2, the major anticancer ingredient of ginsenoside H dripping pills, in healthy subjects

Z Wang, R Liu, L Chen, H Wang, M Zhou… - Clinical …, 2021 - Wiley Online Library
… The results showed that ginsenoside Rh2 was … of ginsenoside Rh2 was approximately
dose‐dependent in terms of AUC and C max . The plasma concentration of ginsenoside Rh2

How does ginsenoside Rh2 mitigate adipogenesis in cultured cells and obese mice?

L Zhang, C Virgous, H Si - Molecules, 2020 - mdpi.com
… lowered fasting blood glucose. These results suggest that ginsenoside Rh2 dose-dependently
inhibits adipogenesis through down-regulating the PPAR-γ pathway, and Rh2 may be a …