Inhalant cannabidiol inhibits glioblastoma progression through regulation of tumor microenvironment

H Khodadadi, ÉL Salles, A Alptekin… - … and Cannabinoid …, 2023 - liebertpub.com
… time, the potential effect of inhaled CBD in the progression of GBM in a murine model, and …
the TME of GBM. Our findings demonstrated the potential of CBD inhalation in the inhibition of …

Altering biomolecular condensates as a potential mechanism that mediates cannabidiol effect on glioblastoma

LP Wang, PS Chagas, ÉL Salles, SE Naeini, J Gouron… - Medical Oncology, 2024 - Springer
… This study investigates whether inhaled CBD may play an intervening role towards SGs in …
-tumor growth effects in inhalant cannabidiol (CBD) via a pre-clinical mouse model of GBM [3]. …

Inhalant cannabidiol impedes tumor growth through decreased tumor stemness and impaired angiogenic switch in NCI-H1437-induced human lung cancer model

ÉL Salles, SE Naeini, H Khodadadi, B Bhandari… - Human Cell, 2023 - Springer
… that cannabidiol (CBD) could impede tumor growth in mouse models of melanoma and
glioblastoma… In this study, we tested, for the first time, inhalant CBD in the treatment of heterotopic …

THE APPLICATION OF CANNABIDIOL IN THE TREATMENT OF GLIOBLASTOMA.

A RYBARCZYK… - Acta Poloniae …, 2023 - search.ebscohost.com
… been demonstrated in GBM cells, the substances affecting its key elements may potentially
inhibit tumor progression. Preclinical models indicate that CBD inhibits GBM tumor growth by …

Cannabinoids in the treatment of glioblastoma

B Buchalska, K Kamińska, M Owe-Larsson… - Pharmacological …, 2024 - Springer
cannabinoid metabolism as well as in the cannabinoid receptor expression. The GBM cells
show expression of cannabinoid … Khodadadi et al. reported inhalant CBD limits GBM growth …

Efficacy of cannabinoids against glioblastoma multiforme: A systematic review

I Kyriakou, N Yarandi, E Polycarpou - Phytomedicine, 2021 - Elsevier
… anticancer properties of cannabinoids from Cannabis sativa. … possess anticancer potencies
against glioma cells, however this … sample sizes are necessitated urgently for GBM treatment. …

From bench to bedside: the application of cannabidiol in glioma

S Feng, Y Pan, P Lu, N Li, W Zhu, Z Hao - Journal of Translational …, 2024 - Springer
… In recent years, cannabidiol (CBD) has … glioma therapy, as well as the current status of
nanomedicine formulations of CBD, and discusses the potential and challenges of CBD in glioma

Concomitant treatment of malignant brain tumours with CBD–a case series and review of the literature

R Likar, M Koestenberger, M Stultschnig… - Anticancer …, 2019 - ar.iiarjournals.org
… Following TMZ treatment after GBM recurrence, only 21% of patients obtain a progression-…
might be effective in glioma therapy (8). Although cannabis including extracts containing …

[HTML][HTML] Case report: clinical outcome and image response of two patients with secondary high-grade glioma treated with chemoradiation, PCV, and cannabidiol

PB Dall'Stella, MFL Docema, MVC Maldaun… - Frontiers in …, 2019 - frontiersin.org
… the fact that THC was often inhaled in the course of the PCV … Studies of CBD in animal
models of glioma reported its anti-… therapeutically exploited for the management of GBM (43, 44)…

Cannabidiol (CBD) in cancer management

K O'Brien - Cancers, 2022 - mdpi.com
… the immune system that characterises glioblastoma. In their research using a mice model
of glioblastoma (using modified glioblastoma cells from humans), inhalation of CBD for seven …