α-Catenin inhibits glioma cell migration, invasion, and proliferation by suppression of β-catenin transactivation

H Ji, J Wang, B Fang, X Fang, Z Lu - Journal of neuro-oncology, 2011 - Springer
… tumor cell migration and invasion [5, 24]. We demonstrate here that β-catenin transactivation
… be regulated by α-catenin and that this regulation affects GBM cell motility and proliferation. …

[HTML][HTML] Expression/activation of α5β1 integrin is linked to the β-catenin signaling pathway to drive migration in glioma cells

G Renner, F Noulet, MC Mercier, L Choulier… - Oncotarget, 2016 - ncbi.nlm.nih.gov
… Activation of cell membrane-associated kinases (growth factor receptors … of glioma) is
thought to disrupt these complexes and to promote beta-catenin transactivation and cell migration […

βCatenin Signalling in Glioblastoma Multiforme and Glioma‐Initiating Cells

M Nager, D Bhardwaj, C Cantí, L Medina… - Chemotherapy …, 2012 - Wiley Online Library
… α-catenin and promotes β-catenin transactivation [40]. Whether the Wnt-induced and growth
factor-induced β-catenin nuclear pools collaborate in glioma cells … promoting cell migration

Nuclear PKM2 regulates β-catenin transactivation upon EGFR activation

W Yang, Y Xia, H Ji, Y Zheng, J Liang, W Huang, X Gao… - Nature, 2011 - nature.com
glioma malignancy and prognosis. These findings reveal that EGF induces β-catenin
transactivation … assays and cell migration assay were performed as previously described 14,21,22 …

[HTML][HTML] EGF-induced ERK activation promotes CK2-mediated disassociation of α-catenin from β-catenin and transactivation of β-catenin

…, J Wang, H Nika, D Hawke, S Keezer, Q Ge, B Fang… - Molecular cell, 2009 - cell.com
… human glioblastoma specimens and with grades of glioma malignancy. This EGFR-ERK-CK2-mediated
phosphorylation of α-catenin promotes β-catenin transactivation and tumor cell

Inactivation of PI3K/AKT signaling inhibits glioma cell growth through modulation of β-catenin-mediated transcription

L Han, Y Yang, X Yue, K Huang, X Liu, P Pu, H Jiang… - Brain research, 2010 - Elsevier
… -catenin pathway. ►We confirmed the cross talk in glioblastoma cells for the first time. … of
PI3K/AKT represses β-catenin-mediated transcription in glioblastoma cells. These findings on …

[HTML][HTML] Crosstalk between β-catenin and CCL2 drives migration of monocytes towards glioblastoma cells

P Aretz, D Maciaczyk, S Yusuf, RV Sorg… - International Journal of …, 2022 - mdpi.com
… Impacts Monocyte Migration and CCL2 Secretion To identify the impact of β-catenin in
glioma cells on immune cell migration, we first established a β-catenin knockdown using small …

Wnt/beta-catenin signaling in glioma

K Zhang, J Zhang, L Han, P Pu, C Kang - Journal of Neuroimmune …, 2012 - Springer
… -catenin nuclear translocation in human glioblastoma cells, thereby enhancing beta-catenin
transactivation … that in EGF treated glioma cells, beta-catenin could be transactivated through …

Nuclear phosphorylated Y142 β-catenin accumulates in astrocytomas and glioblastomas and regulates cell invasion

M Náger, M Santacana, D Bhardwaj, J Valls, I Ferrer… - Cell Cycle, 2015 - Taylor & Francis
… α-catenin phosphorylation, β-catenin transactivation and GBM … the subcellular localization
of β-catenin forms in gliomas, we … β-catenin mutant indicate that HGF promotes cell migration

[HTML][HTML] Overexpressed P75CUX1 promotes EMT in glioma infiltration by activating β-catenin

A Xu, X Wang, J Luo, M Zhou, R Yi, T Huang… - Cell Death & …, 2021 - nature.com
… 3: CUX1 knockdown inhibited cell migration and invasion by regulating EMT progression …
enhancer factor/T-cell factor factors induces the transactivation of target genes, including …