Phosphofructokinase 1 platelet isoform promotes β-catenin transactivation for tumor development
… genes CCND1 and MYC in human glioblastoma cells. Importantly, we showed that EGFR-…
migration and invasion. Given that we measured cell migration at 12 h and cell invasion at …
migration and invasion. Given that we measured cell migration at 12 h and cell invasion at …
Glucocorticoid receptor β regulates injury-mediated astrocyte activation and contributes to glioma pathogenesis via modulation of β-catenin/TCF transcriptional activity
Y Yin, X Zhang, Z Li, L Deng, G Jiao, B Zhang… - Neurobiology of …, 2013 - Elsevier
… It serves in both trans-activation and trans-repression of specific target genes for managing
… that this pathway can promote glioma cell migration and proliferation in combination with …
… that this pathway can promote glioma cell migration and proliferation in combination with …
The unwanted cell migration in the brain: glioma metastasis
XT Qi, JS Zhan, LM Xiao, L Li, HX Xu, ZB Fu… - Neurochemical …, 2017 - Springer
… Migration and infiltration of astrocytes and glioma cells … mechanisms related to glioma cell
migration, including … transition (MET), β-catenin, integrins, cell polarity, cytoskeleton, epidermal …
migration, including … transition (MET), β-catenin, integrins, cell polarity, cytoskeleton, epidermal …
Vasculogenesis and angiogenesis initiation under normoxic conditions through Wnt/β-catenin pathway in gliomas
A Vallée, R Guillevin, JN Vallée - Reviews in the Neurosciences, 2017 - degruyter.com
… -1α, gene transactivation encoding … by glioma cells via the monocarboxylate lactate
transporter-1 up-regulated by HIF-1α and lactate anion activates HIF-1α in normoxic endothelial cells …
transporter-1 up-regulated by HIF-1α and lactate anion activates HIF-1α in normoxic endothelial cells …
β-catenin/Tcf-4 complex transcriptionally regulates AKT1 in glioma
L Chen, K Huang, L Han, Z Shi… - International …, 2011 - spandidos-publications.com
… To test the specificity of the TBE site 6 for transactivation by β-catenin/Tcf-4, TBE6 mutant
and wild-type AKT1 promoter luciferase plasmids were transiently transfected into LN229 and …
and wild-type AKT1 promoter luciferase plasmids were transiently transfected into LN229 and …
Current understanding on EGFR and Wnt/β-catenin signaling in glioma and their possible crosstalk
I Paul, S Bhattacharya, A Chatterjee… - Genes & …, 2013 - journals.sagepub.com
… For example, EGFR activation results in Wnt-independent β-catenin transactivation by …
leading to loss of cell-to-cell contact and increased cell migration. EGFR also induces …
leading to loss of cell-to-cell contact and increased cell migration. EGFR also induces …
Thermodynamics in gliomas: interactions between the canonical WNT/beta-catenin pathway and PPAR gamma
A Vallée, Y Lecarpentier, R Guillevin… - Frontiers in …, 2017 - frontiersin.org
… PI3K/Akt pathway promotes cell survival, cell growth, cell proliferation, cell migration and
angiogenesis in response to extracellular signals including hormones and growth factors. …
angiogenesis in response to extracellular signals including hormones and growth factors. …
MiR-30a-5p is induced by Wnt/β-catenin pathway and promotes glioma cell invasion by repressing NCAM
Z Wang, X Dai, Y Chen, C Sun, Q Zhu, H Zhao… - Biochemical and …, 2015 - Elsevier
… cells, which depends on miR-30a-5p. Finally, we found that miR-30a-5p promotes glioma
cell growth invasion by repressing NCAM. Our findings demonstrate a novel Wnt/β-catenin–…
cell growth invasion by repressing NCAM. Our findings demonstrate a novel Wnt/β-catenin–…
Secreted Frizzled-related proteins inhibit motility and promote growth of human malignant glioma cells
W Roth, C Wild-Bode, M Platten, C Grimmel… - Oncogene, 2000 - nature.com
… of malignant glioma cells in vitro and in vivo and inhibit cellular migration in vitro. … β-catenin
translocates to the nucleus where it serves as a transactivator for the transcription factor T-cell …
translocates to the nucleus where it serves as a transactivator for the transcription factor T-cell …
RBM5 inhibits tumorigenesis of gliomas through inhibition of Wnt/β-catenin signaling and induction of apoptosis
Y Jiang, H Sheng, L Meng, H Yue, B Li, A Zhang… - World journal of surgical …, 2017 - Springer
… Cell migration and invasion were essential for tumor metastasis. Accordingly, we … that
Wnt/β-catenin signaling was activated by RBM5 in gliomas cells. Wnt/β-catenin signaling was one …
Wnt/β-catenin signaling was activated by RBM5 in gliomas cells. Wnt/β-catenin signaling was one …