The impact of upper and lower motor neuron burden on diagnostic certainty, and clinical course of spinal-onset amyotrophic lateral sclerosis: A cluster-based …

G Milella, S Zoccolella, A Giugno, M Filardi, D Urso… - Journal of …, 2023 - Springer
… Upper motor neuron (UMN) and lower motor neuron (LMN) involvement represent the core
… Upper motor neuron burden was evaluated using the Penn Upper Motor Neuron scale (…

Global, regional, and national burden of neurological disorders, 1990-2016: a systematic analysis for the global burden of disease study 2016

M Postma, GBD 2016 Neurology Collaborators - Lancet Neurology, 2019 - research.rug.nl
… When examining individual disorders, a significantly higher burden (as measured by age-…
observed for TBI, Parkinson’s disease, tetanus, motor neuron diseases, and stroke, with male-…

The Swedish motor neuron disease quality registry

E Longinetti, A Regodón Wallin… - … Lateral Sclerosis and …, 2018 - Taylor & Francis
Objective: We set up the Swedish Motor Neuron Disease (MND) Quality Registry to assure
early diagnosis and high-quality health care for all MND patients (mainly amyotrophic lateral …

Targeted assessment of lower motor neuron burden is associated with survival in amyotrophic lateral sclerosis

MS Devine, E Ballard, P O'Rourke… - … Lateral Sclerosis and …, 2016 - Taylor & Francis
… Identifying who will benefit from non-invasive ventilation in amyotrophic lateral sclerosis/motor
neuron disease in a clinical cohort. J Neurol Neurosurg Psychiatry 2015; doi: 10.1136/jnnp…

A systematic review of behavioural changes in motor neuron disease

J Raaphorst, E Beeldman, M De Visser… - Amyotrophic Lateral …, 2012 - Taylor & Francis
… Neuropathological and genetic studies have suggested a disease spectrum with motor
neuron disease (MND) and frontotemporal lobar degeneration (FTLD) on the extreme ends (…

Cerebellar pathology in motor neuron disease: neuroplasticity and neurodegeneration

RH Chipika, G Mulkerrin, PF Pradat… - Neural regeneration …, 2022 - journals.lww.com
Amyotrophic lateral sclerosis is a relentlessly progressive multi-system condition. The
clinical picture is dominated by upper and lower motor neuron degeneration, but extra-motor

Global estimates of the need for rehabilitation based on the Global Burden of Disease study 2019: a systematic analysis for the Global Burden of Disease Study 2019

A Cieza, K Causey, K Kamenov, SW Hanson… - The Lancet, 2020 - thelancet.com
… To estimate the need for rehabilitation, data from the Global Burden of Diseases, Injuries, …
GBD 2019 Diseases and Injuries Collaborators Global burden of 369 diseases and injuries …

Supportive care needs of patients with amyotrophic lateral sclerosis/motor neuron disease and their caregivers: A scoping review

J Oh, JA Kim - Journal of clinical nursing, 2017 - Wiley Online Library
… to motor neuron disease family caregivers, as well as highlight some of the suggested
interventions to alleviate burdenburden and quality-of-life studies on motor neuron disease family …

The management of motor neurone disease

PN Leigh, S Abrahams, A Al-Chalabi… - Journal of Neurology …, 2003 - jnnp.bmj.com
… In our view, there is no justice in excluding patients with a lower motor neurone phenotype
… Non-invasive ventilation in motor neuron disease: current UK practice. Amyotroph Lateral …

Structural and functional brain connectome in motor neuron diseases: a multicenter MRI study

S Basaia, F Agosta, C Cividini, F Trojsi, N Riva… - Neurology, 2020 - AAN Enterprises
… with the disease. Network-based advanced MRI provides an objective in vivo assessment
of motor neuron diseases, delivering potential prognostic markers. Motor neuron diseases (…