… However, the mechanism of this downregulation is unknown. In the present study we have
investigated the down-regulation of the glucocorticoid receptor by glucocorticoids in two …

… of the ideas that have led to the concept of glucocorticoid receptor … current state of knowledge
of glucocorticoid receptor down-regulation … downregulation instead of after down-regulated …

… The data revealed that glucocorticoid receptors exhibited specific binding to their own cDNA…
the down-regulation of glucocorticoid receptors, we analyzed the effect of glucocorticoids on …

… via the binding of the complex to negative glucocorticoid response elements (nGREs), and
… of selective glucocorticoid receptor agonists (SEGRAs) and selective glucocorticoid receptor …

… the rat glucocorticoid receptor (GR) was used to study mechanisms of GR mRNA regulation.
… The down-regulation of GR mRNA levels appears to be independent of protein synthesis, …

… concentration of the glucocorticoid receptor (GR) protein. By regulating the expression of GR
… followed the same pattern, although downregulation was not as pronounced as the down…

… shown to regulate the transcription of some genes, including glucocorticoid receptor itself. …
the expression of mRNA for glucocorticoid receptor in human blood monocytes obtained from …

… Glucocorticoid receptor mRNA concentrations in response to glucocorticoid treatment have
… In this report we examined the ligand-induced down-regulation of glucocorticoid receptors …

… use of a mutant glucocorticoid receptor and steroidal … glucocorticoid receptor mutant that
does not enhance the IκBα level is still able to repress NF‐κB activity. Conversely, glucocorticoid …

… This ligand-induced, receptor-mediated event consequently limits the span of cellular … to
glucocorticoids. In the last decade, the molecular mechanisms underlying GR down regulation …