[PDF][PDF] The pivotal role of glucose metabolism in determining oocyte developmental competence

ML Sutton-McDowall, RB Gilchrist, JG Thompson - Reproduction, 2010 - researchgate.net
… This review will discuss the relevant pathways of glucose metabolism by COCs during in …
of the COC to glucose metabolism. The consequences of exposing COCs to abnormal glucose

Metabolism of radiolabeled glucose by mouse oocytes and oocyte-cumulus cell complexes

SM Downs, AM Utecht - Biology of reproduction, 1999 - academic.oup.com
… used to measure glucose metabolism in this study is unlike that usually employed in our
laboratory for experiments on oocyte maturation. In most experiments, oocytes are cultured in …

Effects of glucose metabolism during in vitro maturation on cytoplasmic maturation of mouse oocytes

HL Xie, YB Wang, GZ Jiao, DL Kong, Q Li, H Li… - Scientific reports, 2016 - nature.com
oocyte nuclear maturation but only a limited blastocyst formation without glucose, this study
determined effects of glucose metabolism … cumulus-oocyte-complexes (COCs) with glucose, …

The influence of glucose, cumulus cells, and metabolic coupling on ATP levels and meiotic control in the isolated mouse oocyte

SM Downs - Developmental biology, 1995 - Elsevier
… the inhibitory effect of glucose on oocyte maturation (91 and … nadotropin revealed that a
decrease in oocyte ATP preceded or … study indicate that glucose-derived elevation of oocyte ATP …

Glucose metabolism during in vitro maturation of mouse oocytes: An study using RNA interference

HL Xie, S Zhu, J Zhang, J Wen, HJ Yuan… - Journal of Cellular …, 2018 - Wiley Online Library
oocytes (DOs). In this study, RNAi was adopted to specify the effects of glucose metabolism
in CCs or DOs on oocyte … dehydrogenase (GAPDH) or glucose-6-phosphate dehydrogenase …

Glucose metabolism in mouse cumulus cells prevents oocyte aging by maintaining both energy supply and the intracellular redox potential

Q Li, DQ Miao, P Zhou, YG Wu, D Gao… - Biology of …, 2011 - academic.oup.com
… how intermediary metabolism regulates the oocyte redox potential. In the present study, we
examined glucose metabolism using the postovulatory aging mouse oocyte model, with an …

Hyperglycaemia and lipid differentially impair mouse oocyte developmental competence

SL Wong, LL Wu, RL Robker… - Reproduction …, 2015 - CSIRO Publishing
oocyte metabolism. In order to begin to understand how both glucose and lipid metabolic
disruptions influence oocyte … present study we exposed mouse cumulus–oocyte complexes to …

[PDF][PDF] Fatty acid metabolism during maturation affects glucose uptake and is essential to oocyte competence

M Paczkowski, WB Schoolcraft, RL Krisher - Reproduction, 2014 - scholar.archive.org
glucose metabolism are related to the mouse COC, as inhibition of FAO increases glucose
… The findings of this study have further clarified the role of lipids during mouse oocyte

Glucose utilization during gonadotropin‐induced meiotic maturation in cumulus cell‐enclosed mouse oocytes

SM Downs, PG Humpherson… - Molecular …, 1996 - Wiley Online Library
… In addition, when we assayed denuded mouse oocytes for HK in numbers equal to or
greater than those of complexes, no activity was observed. Thus, the activity detected using …

Comparative importance of fatty acid beta-oxidation to nuclear maturation, gene expression, and glucose metabolism in mouse, bovine, and porcine cumulus oocyte …

M Paczkowski, E Silva, WB Schoolcraft… - Biology of …, 2013 - academic.oup.com
… Completion of oocyte nuclear maturation was inhibited after COC exposure to 250 … mouse
oocytes, 100 μM etomoxir in bovine oocytes, and as little as 10 μM etomoxir in porcine oocytes