GLUT4 exocytosis

J Stöckli, DJ Fazakerley, DE James - Journal of cell science, 2011 - journals.biologists.com
… They provide storage and exocytic functions for GLUT4 and a handful of other proteins, such
as IRAP, thereby enabling transient regulation of nutrient intake into muscle and fat cells on …

[PDF][PDF] Intracellular organization of insulin signaling and GLUT4 translocation

RT Watson, JE Pessin - Recent progress in hormone research, 2001 - endocrine.org
… membrane, GLUT4 transporter proteins are sequestered into specialized storage vesicles
… that ultimately result in the translocation of the GLUT4 storage compartments to the plasma …

Ins (endocytosis) and outs (exocytosis) of GLUT4 trafficking

JC Hou, JE Pessin - Current opinion in cell biology, 2007 - Elsevier
GLUT4 is stored in a poorly characterized intracellular vesicular … synthesized GLUT4 into
the specialized compartment. Insulin-stimulated GLUT4 translocation from this compartment to …

[HTML][HTML] Insulin releases Glut4 from static storage compartments into cycling endosomes and increases the rate constant for Glut4 exocytosis

JM Muretta, I Romenskaia, CC Mastick - Journal of Biological Chemistry, 2008 - ASBMB
Glut4 to the plasma membrane by increasing the rate of Glut4 exocytosis (through an
increase in the exocytic rate constant k ex ) while simultaneously decreasing the rate of Glut4

Moving GLUT4: the biogenesis and trafficking of GLUT4 storage vesicles

S Rea, DE James - Diabetes, 1997 - Am Diabetes Assoc
… the translocation of GLUT4 from an intracellular storage … to suggest that the GLUT4 storage
compartment moves directly to … that the GLUT4 storage compartment be referred to as GLUT4

Endocytosis, recycling, and regulated exocytosis of glucose transporter 4

K Foley, S Boguslavsky, A Klip - Biochemistry, 2011 - ACS Publications
translocation of GLUT4 to the PM from a specialized compartment termed GLUT4 storage
Although the entire process has been classically called GLUT4 translocation, we here break it …

The mass action hypothesis: formation of Glut4 storage vesicles, a tissue‐specific, regulated exocytic compartment

PF Pilch - Acta physiologica, 2008 - Wiley Online Library
storage vesicles (GSVs). The GSVs represent a tissue-specific compartment that is an ultimate
target of the insulin signalling cascade. Glut4 translocation has been extensively studied …

Moving the insulin-regulated glucose transporter GLUT4 into and out of storage

GD Holman, IV Sandoval - Trends in cell biology, 2001 - cell.com
… isoform GLUT4 is unique … a storage compartment. In insulin-sensitive cells, such as fat and
muscle, insulin stimulation leads to release of GLUT4 from this reservoir and its translocation

[HTML][HTML] Isolation and characterization of the two major intracellular Glut4 storage compartments

TA Kupriyanova, V Kandror, KV Kandror - Journal of Biological Chemistry, 2002 - ASBMB
… thus represent the major compartments of Glut4 storage and translocation in the living cell. …
be delivered to a cellugyrin-negative Glut4-containing compartment, we carried out two types …

Subcellular compartmentalization and trafficking of the insulin-responsive glucose transporter, GLUT4

RT Watson, JE Pessin - Experimental cell research, 2001 - Elsevier
… PKB, and PKC / to GLUT4 translocation. Progress in this area will … of GLUT4 from this
specialized storage compartment to the … for the storage and retention of GLUT4 in this …