… in glutamate-evoked excitotoxicity. We show first that the delayed deregulation of cellular
CaZ+ homeostasis following glutamate … ; second, that glutamate-dependent deregulation can …

… In this article we investigate the contribution played by ROS generation in the phenomenon
of granule cell DCD. It is found that the glutamate-dependent component of ROS production …

… We have observed previously that the total 45 Ca 2+ accumulation of granule cells exposed
to glutamate for 20 min is decreased in cells with depolarized mitochondria. Figure2 shows …

… granule cells exposed to glutamate. To interpret the single-cell fluorescence response of cells
… Glutamate usually caused an immediate decrease in Δψ m of <10 mV, attributable to Ca 2…

… The role of mitochondria in the control of glutamate excitotoxicity is investigated. The response
of cultured cerebellar granule cells to continuous glutamate exposure is characterised by …

… cells. In conclusion, NO donors protect cultured cerebellar granule cells from glutamate-induced
cell … ] i increase, and glial cells provide negligible protection against glutamate-induced …

… GSH plays a very important role in protecting neurones from free radical injury following
the extracellular release of glutamic acid. This process is applicable to cerebellar …

… granule cells, the most abundant neuronal subtype in the mammalian brain, functionally
express different forms of glutamate … event in glutamate-evoked neuronal excitotoxicity is an …

… The major finding of the present study is that in cerebellar granule cells, the property of
PKC-associated mGluRs in inhibiting glutamate responses relies on the presence of the NR2C …

… The in vitro model we study is the rat cerebellar granule cell in primary culture and its
susceptibility to NMDA receptor-mediated necrosis, which is preceded by a delayed failure of …