Neuroprotective effects of regulators of the glycogen synthase kinase-3β signaling pathway in a transgenic model of Alzheimer's disease are associated with reduced …

E Rockenstein, M Torrance, A Adame… - Journal of …, 2007 - Soc Neuroscience
… However it is not known whether blocking GSK3β signaling is neuroprotective and ameliorates
… We found that the neuroprotective effects of blocking GSK3β in vivo was associated with …

Synergistic neuroprotective effects of lithium and valproic acid or other histone deacetylase inhibitors in neurons: roles of glycogen synthase kinase-3 inhibition

Y Leng, MH Liang, M Ren, Z Marinova… - Journal of …, 2008 - Soc Neuroscience
… caused synergistic neuroprotectionneuroprotective effects of lithium and HDAC inhibitors
and suggest that GSK-3 inhibition is a likely molecular target for the synergistic neuroprotection

Neuroprotective effect of hemeoxygenase-1/glycogen synthase kinase-3β modulators in 3-nitropropionic acid-induced neurotoxicity in rats

A Khan, S Jamwal, KRV Bijjem, A Prakash, P Kumar - Neuroscience, 2015 - Elsevier
The present study has been designed to explore the possible interaction between
hemeoxygenase-1 (HO-1) and glycogen synthase kinase-3β (GSK-3β) pathway in 3-nitropropionic …

Glycogen synthase kinase‐3β, mood stabilizers, and neuroprotection

X Li, GN Bijur, RS Jope - Bipolar disorders, 2002 - Wiley Online Library
… of lithium (eg, [37–41]), and some reported evidence for neuroprotection by VPA [42,43], and
LTG [44–46], by identifying a specific mechanism contributing to their neuroprotective effects

The neuroprotective effect of lithium chloride on cognitive impairment through glycogen synthase kinase-3β inhibition in intracerebral hemorrhage rats

Z Liu, R Li, C Jiang, S Zhao, W Li, X Tang - European journal of …, 2018 - Elsevier
… disorder, has shown neuroprotective effects through glycogen synthase kinase-3β … glycogen
synthase kinase-3β activity. Our results showed lithium chloride inhibited glycogen synthase

[HTML][HTML] The Role of Glycogen Synthase Kinase-3β in the Zinc-Mediated Neuroprotective Effect of Metformin in Rats with Glutamate Neurotoxicity

A Oruc, KY Oruc, K Yanar, M Mengi, A Caglar… - … Trace Element Research, 2024 - Springer
… Metformin has been suggested to have protective effects on … effects of metformin and the
inhibition of glycogen synthase … whether the effects of metformin on neuroprotection and …

… , a Phlorotannin Extracted from Ecklonia maxima, Produces Anti-β-amyloid Oligomer Neuroprotective Effects Possibly via Directly Acting on Glycogen Synthase …

J Wang, J Zheng, C Huang, J Zhao, J Lin… - ACS chemical …, 2018 - ACS Publications
… in the ATP binding site of glycogen synthase kinase 3β and mitogen activated protein kinase…
might produce neuroprotective effects via concurrent inhibition of glycogen synthase kinase …

Neuroprotective effects of atypical D1 receptor agonist SKF83959 are mediated via D1 receptor‐dependent inhibition of glycogen synthase kinase‐3β and a receptor …

Y Yu, JR Wang, PH Sun, Y Guo… - Journal of …, 2008 - Wiley Online Library
… of SKF83959 and its potential mechanism for the effect in cultured rat cortical cells. … glycogen
synthase kinase-3β (GSK-3β) which was associated with the drug’s neuroprotective effect, …

Glycogen synthase kinase-3 in neurodegeneration and neuroprotection: lessons from lithium

S Yadranji Aghdam, SW Barger - Current Alzheimer Research, 2007 - ingentaconnect.com
… The neuroprotective actions of lithium have begun to be tested for their more specific …
Lithium showed neuroprotective effects against neurotoxicity induced by MPTP (N-methyl-4-phenyl-…

[HTML][HTML] The Akt/glycogen synthase kinase-3β pathway participates in the neuroprotective effect of interleukin-4 against cerebral ischemia/reperfusion injury

M Li, WW Gao, L Liu, Y Gao, YF Wang… - Neural regeneration …, 2020 - journals.lww.com
… , the IL-4-induced neuroprotective effect in IR was blocked by the Akt inhibitor LY294002.
Thus, these results demonstrate that IL-4 pretreatment could exert neuroprotective effects by …